P2139
聚（乙二醇）
average MN 8,000, hydroxyl
别名:
PEG
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关于此项目
线性分子式:
H(OCH2CH2)nOH
化学文摘社编号:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
产品名称
聚（乙二醇）, average mol wt 8,000, powder
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
form
powder
mol wt
average mol wt 8,000
Quality Level
greener alternative product characteristics
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
solubility
water: soluble (PEG is soluble in water approximately 630 mg/ml, 20 °C)
density
1.0845 g/mL at 70 °C
1.0689 g/mL at 90 °C
Ω-end
hydroxyl
α-end
hydroxyl
greener alternative category
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Application
聚乙二醇可用于药物制剂，提高药物的溶出率和口服生物利用度。
聚乙二醇可用于高效分离抗癌和抗炎性优异的食用纳米颗粒(ENP)。聚乙二醇是一种拥挤剂(crowding agent)，可形成网状网捕获和沉淀纳米囊泡。例如，PEG法可分离姜来源ENP，比超速离心法更加经济实惠。
PEG可作为前体合成可降解水凝胶，用于亲水性高分子药物控释。
聚乙二醇可用于高效分离抗癌和抗炎性优异的食用纳米颗粒(ENP)。聚乙二醇是一种拥挤剂(crowding agent)，可形成网状网捕获和沉淀纳米囊泡。例如，PEG法可分离姜来源ENP，比超速离心法更加经济实惠。
PEG可作为前体合成可降解水凝胶，用于亲水性高分子药物控释。
Features and Benefits
- 高结构柔性
- 生物相容性
- 两亲性
- 高水化性
- 无空间位阻
General description
聚乙二醇（PEG）是一种亲水性聚合物。它可以通过环氧乙烷的阴离子开环聚合进行合成，从而形成不同分子量和带有各种不同端基的聚合物。当交联成网络时，PEG可具有高含水量，从而形成“水凝胶”。由于它不会引发免疫反应，因此PEG是一种适合生物学应用的材料
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
D E Corpet et al.
Cancer research, 60(12), 3160-3164 (2000-06-24)
We have previously shown that dietary polyethylene-glycol (PEG) suppresses the occurrence of azoxymethane-induced cancers in an accelerated rat model of colon carcinogenesis. To determine the consistency of this preventive effect, we carried out a long-term study in rats fed the
Parveen K Garg et al.
Atherosclerosis, 297, 81-86 (2020-02-26)
We aimed to assess the relationship of HDL (high-density lipoprotein)-mediated cholesterol mass efflux capacity (CMEC) with risk of incident peripheral artery disease (PAD). CMEC was measured in 1458 Multi-Ethnic Study of Atherosclerosis participants between 2000 and 2002 as part of
Maofu Li et al.
BMC plant biology, 21(1), 57-57 (2021-01-23)
Strawberry (Fragaria × ananassa Duch.) is an important fruit crop worldwide. It was particularly sensitive to drought stress because of their fibrous and shallow root systems. Mutant rty of Arabidopsis thaliana ROOTY (RTY) results in increased endogenous auxin levels, more
Leslie Y Beh et al.
Cell, 177(7), 1781-1796 (2019-05-21)
DNA N6-adenine methylation (6mA) has recently been described in diverse eukaryotes, spanning unicellular organisms to metazoa. Here, we report a DNA 6mA methyltransferase complex in ciliates, termed MTA1c. It consists of two MT-A70 proteins and two homeobox-like DNA-binding proteins and
Lisa F Horowitz et al.
Lab on a chip, 21(1), 122-142 (2020-11-12)
As preclinical animal tests often do not accurately predict drug effects later observed in humans, most drugs under development fail to reach the market. Thus there is a critical need for functional drug testing platforms that use human, intact tissues
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