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经验公式(希尔记法):
C15H10O2
化学文摘社编号:
分子量:
222.24
EC Number:
201-454-4
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1911699
MDL number:
Assay:
97%
Form:
crystals
InChI key
NFBAXHOPROOJAW-UHFFFAOYSA-N
InChI
1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H
SMILES string
O=C1C(c2ccccc2)C(=O)c3ccccc13
assay
97%
form
crystals
Gene Information
human ... VKORC1(79001)
mp
144-148 °C (lit.)
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Skin Sens. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Céline Verstuyft et al.
Clinical pharmacokinetics, 51(1), 41-53 (2011-12-14)
Vitamin K epoxide reductase complex, subunit 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) polymorphisms are taken into account when predicting a safe oral dose of coumarin anticoagulant therapy, but little is known about the effects of genetic predictors on the
E Comets et al.
Clinical pharmacology and therapeutics, 91(5), 777-786 (2012-04-05)
In the PREPA observational study, we investigated the factors influencing pharmacokinetic and pharmacodynamic variability in the responses to fluindione, an oral anticoagulant drug, in a general population of octogenarian inpatients.Measurements of fluindione concentrations and international normalized ratio (INR ) were
Ronald Lg Flumignan et al.
The Cochrane database of systematic reviews, 10, CD013739-CD013739 (2021-01-28)
Coronavirus disease 2019 (COVID-19) is a serious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The primary manifestation is respiratory insufficiency that can also be related to diffuse pulmonary microthrombosis in people with COVID-19. This disease also causes
M Bezier et al.
Annales de dermatologie et de venereologie, 138(10), 657-663 (2011-10-08)
Vitamin K antagonists (VKAs) are widely used in thromboembolic diseases. We report five cases of necrotic leg ulcers having a particularly severe course and in which withdrawal of VKA treatment alone enabled healing. Five patients presented with necrotic leg ulcers
Eric Pautas et al.
Geriatrie et psychologie neuropsychiatrie du vieillissement, 9(2), 171-177 (2011-06-22)
Vitamin K antagonist tablets are often split to fractionate the dose by elderly patients. We performed a study in order to assess the divisibility of one dosage strength of score-lined warfarin and of score-lined fluindione. Due to a recent change
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