P38803
邻苯二甲酰肼
ReagentPlus®, 99%
别名:
双酮酞嗪
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关于此项目
经验公式（希尔记法）:
C8H6N2O2
化学文摘社编号:
分子量:
162.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
215-893-4
MDL number:
Assay:
99%
Form:
solid
产品名称
邻苯二甲酰肼, ReagentPlus®, 99%
InChI key
KGLPWQKSKUVKMJ-UHFFFAOYSA-N
InChI
1S/C8H6N2O2/c11-7-5-3-1-2-4-6(5)8(12)10-9-7/h1-4H,(H,9,11)(H,10,12)
SMILES string
O=C1NNC(=O)c2ccccc12
product line
ReagentPlus®
assay
99%
form
solid
mp
>300 °C (lit.)
Quality Level
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Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
J Schiller et al.
Free radical research, 30(1), 45-57 (1999-04-08)
The reactivity of 5-amino-2,3-dihydro-phthalazine-1,4-dione (luminol) and phthalic hydrazide with hydroxyl radicals was studied. HO*-radicals were generated by the Fenton reaction as well as by water radiolysis. Both luminol and phthalic hydrazide react with hydroxyl radicals under intense chemiluminescence (CL) emission.
I H Hall et al.
The Journal of pharmacy and pharmacology, 41(6), 394-397 (1989-06-01)
The disposition of [14C]2,3-dihydrophthalazine-1,4-dione, a potent hypolipidaemic agent, has been determined after both intravenous and oral administration. Both the routes of administration afforded multi-exponential disposition with an estimated t1/2 of approximately 75 h. After oral administration, the drug was observed
L Butner et al.
International journal of tissue reactions, 18(2-3), 47-55 (1996-01-01)
2,3-Dihydrophthalazine-1,4-diones were observed to be potent anti-inflammatory agents as well as capable of protecting against endotoxin shock in mice at 8 mg/kg i.p. These agents blocked both locally- and centrally-induced pain at 8 mg/kg i.p. In part they appear to
I H Hall et al.
Biomedica biochimica acta, 47(4-5), 423-433 (1988-01-01)
2,3-Dihydrophthalazine-1,4-dione effectively lowers serum levels of cholesterol and triglycerides in Sprague Dawley rats after two weeks, after which the cholesterol levels continued to decline. The maximum serum lipid lowering effect on cholesterol or triglyceride levels was during the seventh and
I H Hall et al.
Anti-cancer drugs, 3(1), 55-62 (1992-02-01)
2,3-Dihydrophthalazine-1,4-dione derivatives demonstrated potent cytotoxicity against the growth of murine leukemia cells and human single cell suspension, i.e. Tmolt3 leukemia and HeLa-S3, as well as colon adenocarcinoma and KB nasopharynx. However, only select compounds demonstrated activity against bronchogenic lung, osteosarcoma
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