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P49007

胡椒碱

≥97%

别名:

1-胡椒酰哌啶

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关于此项目

经验公式（希尔记法）:
C17H19NO3
化学文摘社编号:
94-62-2
分子量:
285.34
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24898568
EC Number:
202-348-0
Beilstein/REAXYS Number:
90741
MDL number:
MFCD00005839
Assay:
≥97%
Form:
crystalline, powder, crystals or chunks, solid
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Quality Level

100

assay

≥97%

form

crystalline, powder, crystals or chunks, solid

mp

131-135 °C (lit.)

SMILES string

O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3

InChI

1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+

InChI key

MXXWOMGUGJBKIW-YPCIICBESA-N

Gene Information

human ... CYP3A4(1576)

Application

Reactant for synthesis of:
  • Dimeric amide alkaloids
  • Piperoyl-amino acid conjugates used for antileishmanial activity
  • Piperine derived amides with TRPV1 activity
  • Piperine analogues as S. aureus NorA efflux pump inhibitors
  • Bioactive conjugates of curcumin with antimicrobial and antiproliferative properties
  • Piperine derivatives for use as trypanocidal agents

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pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SHBT5671
SHBR5704
0000252596
0000252589
0000231403

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Jiu-Wang Yu et al.
Molecular diversity, 25(1), 233-248 (2020-03-05)
Piperine is the main active component of Piper longum L., which is also the main component of anti-sciatica Mongolian medicine Naru Sanwei pill. It has many pharmacological activities such as anti-inflammatory and immune regulation. This paper aims to preliminarily explore
V. R. S. Rao, et al.,
Tetrahedron, 67, 1885-1892 (2011)
Welisson da Silva Ferreira et al.
Bioorganic & medicinal chemistry, 16(6), 2984-2991 (2008-01-30)
We herein describe the synthesis and characterization of nine new 1,3,4-thiadiazolium-2-phenylamine chlorides derived from natural piperine. We evaluate their toxic effects against the different evolutive forms of Trypanosoma cruzi, and the host cell (murine macrophages). The results obtained show that
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全球贸易项目编号

货号GTIN
P49007-1G04061834375333
P49007-5G04061834375364