P50919
炔丙基胺 盐酸盐
95%
别名:
2-丙炔胺 盐酸盐, 3-氨基-1-丙炔 盐酸盐
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关于此项目
线性分子式:
HC≡CCH2NH2 · HCl
化学文摘社编号:
分子量:
91.54
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
239-440-5
Beilstein/REAXYS Number:
3669858
MDL number:
Assay:
95%
Form:
powder
InChI
1S/C3H5N.ClH/c1-2-3-4;/h1H,3-4H2;1H
InChI key
IKXNIQJDNKPPCH-UHFFFAOYSA-N
SMILES string
Cl.NCC#C
assay
95%
form
powder
reaction suitability
reaction type: click chemistry
mp
179-182 °C (lit.)
storage temp.
2-8°C
Quality Level
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Thomas Hermanns et al.
Life science alliance, 3(9) (2020-07-29)
Deubiquitinating enzymes (DUBs) are important regulators of the posttranslational protein ubiquitination system. Mammalian genomes encode about 100 different DUBs, which can be grouped into seven different classes. Members of other DUB classes are found in pathogenic bacteria, which use them
Orit Bar-Am et al.
Journal of Alzheimer's disease : JAD, 21(2), 361-371 (2010-06-18)
The anti-Parkinsonian, irreversible, selective monoamine oxidase (MAO)-B inhibitors, selegiline (deprenyl, (R)-N-methyl-N-(1-phenylpropan-2-yl) prop-2-yn-1-amine) and rasagiline (Azilect, N-propargyl-1(R)-aminoindan), have been proven to possess neuroprotective/neurorestorative activities in cell cultures and animal models of neurodegenerative diseases. Structure-activity studies provide evidence that neuroprotection is associated
Olga P Pereshivko et al.
Organic letters, 12(11), 2638-2641 (2010-05-06)
An efficient, microwave-assisted Cu(I)-catalyzed one-pot coupling of a ketone, an alkyne, and a primary amine (KA(2) coupling) is described, giving access to secondary propargylamines.
Parminder Kaur et al.
Organic & biomolecular chemistry, 8(5), 1091-1096 (2010-02-19)
A variety of substituted chiral propargylamines have been synthesized by reacting chiral N-phosphonylimines with lithium aryl/alkyl acetylides. Seventeen examples were studied to give excellent yields (>90%) and diastereoselectivities (96 : 4 to 99 : 1). It was found that the
The marriage of organocatalysis with metal catalysis: access to multisubstituted chiral 2,5-dihydropyrroles by cascade iminium/enamine-metal cooperative catalysis.
Wangsheng Sun et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(50), 13958-13962 (2011-11-19)
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