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Merck
CN

QBD10203

TFP-dPEG®4-biotinidase resistant biotin

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关于此项目

经验公式(希尔记法):
C31H44F4N4O9S
分子量:
724.76
UNSPSC Code:
51171641
PubChem Substance ID:
NACRES:
NA.22
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InChI

1S/C31H44F4N4O9S/c1-2-21(37-24(40)6-4-3-5-23-28-22(18-49-23)38-31(43)39-28)30(42)36-8-10-45-12-14-47-16-15-46-13-11-44-9-7-25(41)48-29-26(34)19(32)17-20(33)27(29)35/h17,21-23,28H,2-16,18H2,1H3,(H,36,42)(H,37,40)(H2,38,39,43)

InChI key

IOOKENPHEAMTTM-UHFFFAOYSA-N

SMILES string

O=C1NC(C2N1)CSC2CCCCC(NC(C(NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O)=O)CC)=O

assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: amine reactive, reagent type: linker

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

Features and Benefits

TFP-dPEG®4-biotinidase resistant biotin contains an amine reactive TFP ester and chemically modified biotin that is stable in the presence of biotinidase. Resistance to biotinidase cleavage of biotin is necessary in some biotechnology applications. The chemical modification to biotin imparts resistance to biotinidase cleavage without reducing the strength of biotin-avidin binding. The single molecular weight dPEG® spacer imparts water solubility, prevents aggregation and precipitation of labeled peptides and proteins, and reduces non-specific binding. Two different single molecular weight dPEG® spacers are available for precise spatial control between the modified biotin and the surface of the molecule to which it is conjugated.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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