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Merck
CN

QBD10289

m-dPEG®12-MAL

别名:

Polyethylene glycol

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关于此项目

经验公式(希尔记法):
C32H58N2O15
化学文摘社编号:
分子量:
710.81
UNSPSC Code:
51171641
PubChem Substance ID:
NACRES:
NA.22
MDL number:
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InChI

1S/C32H58N2O15/c1-38-8-9-40-12-13-42-16-17-44-20-21-46-24-25-48-28-29-49-27-26-47-23-22-45-19-18-43-15-14-41-11-10-39-7-5-33-30(35)4-6-34-31(36)2-3-32(34)37/h2-3H,4-29H2,1H3,(H,33,35)

InChI key

OVCDVKBUIQUWMR-UHFFFAOYSA-N

SMILES string

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O

assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: sulfhydryl reactive, reagent type: linker
reactivity: thiol reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

Features and Benefits

The m-dPEG®12-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®12-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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