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S3003

芝麻酚

Name: 芝麻酚
Brand: ALDRICH

98%

别名:

3,4-二亚甲氧基苯酚, 3,4-亚甲二氧基苯酚

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关于此项目

经验公式（希尔记法）:

C₇H₆O₃

化学文摘社编号:

533-31-3

分子量:

138.12

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24899539

EC Number:

208-561-5

Beilstein/REAXYS Number:

127405

MDL number:

MFCD00005827

Assay:

98%

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Quality Level

100

assay

98%

mp

62-65 °C (lit.)

SMILES string

Oc1ccc2OCOc2c1

InChI

1S/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2

InChI key

LUSZGTFNYDARNI-UHFFFAOYSA-N

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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ApoE-Dependent Protective Effects of Sesamol on High-Fat Diet-Induced Behavioral Disorders: Regulation of the Microbiome-Gut-Brain Axis.

Tian Yuan et al.

Journal of agricultural and food chemistry, 67(22), 6190-6201 (2019-05-24)

Sesamol, an antioxidant lignan from sesame oil, possesses neuroprotective bioactivities. The present work was aimed to elucidate the systemic protective effects of sesamol on cognitive deficits and to determine the possible link between gut and brain. Wildtype and ApoE-/- mice

DNA interaction studies of sesamol (3,4-methylenedioxyphenol) food additive.

Soheila Kashanian et al.

Molecular biology reports, 40(2), 1173-1179 (2012-10-17)

The interaction of native calf thymus DNA (CT-DNA) with sesamol (3,4-methylenedioxyphenol) in Tris-HCl buffer at neutral pH 7.4 was monitored by absorption spectrophotometry, viscometry and spectrofluorometry. It is found that sesamol molecules could interact with DNA outside and/or groove binding

Sesamol inhibits UVB-induced ROS generation and subsequent oxidative damage in cultured human skin dermal fibroblasts.

S Ramachandran et al.

Archives of dermatological research, 302(10), 733-744 (2010-08-11)

The exposure of cells to ultraviolet B radiation (UVB) can induce the production of reactive oxygen species (ROS) which damage cellular components. Free radical scavengers and antioxidants can interfere with the production of ROS. We studied cytotoxicity, intracellular ROS levels

A novel role of sesamol in inhibiting NF-κB-mediated signaling in platelet activation.

Chao-Chien Chang et al.

Journal of biomedical science, 18, 93-93 (2011-12-16)

Platelet activation is relevant to a variety of coronary heart diseases. Our previous studies revealed that sesamol possesses potent antiplatelet activity through increasing cyclic AMP formation. Although platelets are anucleated cells, they also express the transcription factor, NF-κB, that may

Therapeutic sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome in rats by inhibiting matrix metalloproteinase-9.

Srinivasan Periasamy et al.

Cell biochemistry and biophysics, 61(2), 327-336 (2011-06-18)

We investigated the therapeutic effect of sesamol against monocrotaline-induced sinusoidal obstruction syndrome (SOS) in rats. Male Sprague-Dawley rats were gavaged with a single dose of monocrotaline (90 mg/kg) to induce SOS. Sesamol (5, 10, 20, and 40 mg/kg) was subcutaneously

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全球贸易项目编号

货号	GTIN
S3003-25G-A	04061836920814
S3003-5G-A	04061836920852

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