S3836
精胺
98%
别名:
N,N′-双(3-氨基丙基)-1,4-丁二胺, 精素, 肌胺, 肝胺
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线性分子式:
NH2(CH2)3NH(CH2)4NH(CH2)3NH2
化学文摘社编号:
分子量:
202.34
EC Number:
200-754-2
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
1750791
InChI
1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2
InChI key
PFNFFQXMRSDOHW-UHFFFAOYSA-N
SMILES string
[H]N(CCCN)CCCCN([H])CCCN
assay
98%
bp
150 °C/5 mmHg (lit.)
mp
28-30 (lit.)
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Biochem/physiol Actions
多胺位点混合型 NMDA 受体激动剂/拮抗剂。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
多胺位点混合型 NMDA 谷氨酸受体激动剂/拮抗剂。在高浓度 (1mM) 下观察到神经保护作用，而在低浓度下则观察到神经毒性。它在番木鳖碱-不敏感性甘氨酸位点能够增强激动剂效应。在细胞增殖和分化中发挥作用；抑制神经元一氧化氮合成酶 (nNOS)。
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