T111
8-(二乙氨基)辛基-3,4,5-三甲氧基苯甲酸酯 盐酸盐
≥98%
别名:
TMB-8 · HCl
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关于此项目
线性分子式:
(CH3O)3C6H2CO2(CH2)8N(C2H5)2 · HCl
化学文摘社编号:
分子量:
431.99
Beilstein:
5466611
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
≥98%
表单
powder
mp
94-97 °C (lit.)
SMILES字符串
Cl[H].CCN(CC)CCCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1
InChI
1S/C22H37NO5.ClH/c1-6-23(7-2)14-12-10-8-9-11-13-15-28-22(24)18-16-19(25-3)21(27-5)20(17-18)26-4;/h16-17H,6-15H2,1-5H3;1H
InChI key
KFJZVXKPPQIYCG-UHFFFAOYSA-N
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应用
- 丙型肝炎病毒生命周期的药理活性抑制剂
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Hiroaki Tosuji et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 147(2), 432-437 (2007-02-24)
During meiosis in oocytes of the starfish, Asterina pectinifera, a Ca(2+) transient has been observed. To clarify the role of Ca(2+) during oocyte maturation in starfish, an intracellular Ca(2+) blocker, TMB-8, was applied. The oocyte maturation induced by 1-methyladenine (1-MA)
Pierre Poutrain et al.
Journal of experimental botany, 60(4), 1387-1398 (2009-02-17)
Calcium-mediated signalling is ubiquitous in both animals and plants. Changes in cytoplasmic free Ca(2+) concentration couple diverse arrays of stimuli to their specific responses, the specificity of the stimulus being determined by integrated actions between multiple Ca(2+) mobilization pathways. In
P Fang et al.
Acta physiologica (Oxford, England), 199(1), 53-61 (2010-01-20)
The aim of this study was to determine the effects of motilin on [Ca(2+)](i) regulation and its underlying molecular mechanism in cultured antral smooth muscle cells (ASMCs). Antral cells were isolated and cultured from neonatal rats, and then the [Ca(2+)](i)
Byung-Hwan Lee et al.
Neuropharmacology, 52(4), 1139-1150 (2007-01-30)
We previously demonstrated that 20(S)-ginsenoside Rg(3) (Rg(3)), one of the active components of Panax ginseng, non-competitively inhibits 5-HT(3A) receptor channel activity on extracellular side of the cell. Here, we sought to elucidate the molecular mechanisms underlying Rg(3)-induced 5-HT(3A) receptor regulation.
María Angeles Sánchez-Sampedro et al.
Journal of plant physiology, 162(10), 1177-1182 (2005-11-01)
Elimination of calcium ions from the medium of cell cultures of Silybum marianum (L.) Gaertn increased flavonolignan production. Silymarin accumulation was not altered by treatment of cultures with the calcium ionophore A23187. The specific Ca2+ chelator, EGTA, enhanced the silymarin
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