T90301
3-(2-羟乙基)吲哚
97%
别名:
2-（3-吲哚基）乙醇, 3-吲哚乙醇, IEA, NSC 3884, 色醇
质量水平
方案
97%
mp
56-59 °C (lit.)
SMILES字符串
OCCc1c[nH]c2ccccc12
InChI
1S/C10H11NO/c12-6-5-8-7-11-10-4-2-1-3-9(8)10/h1-4,7,11-12H,5-6H2
InChI key
MBBOMCVGYCRMEA-UHFFFAOYSA-N
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应用
作为反应物用于制备：
- RNA聚合酶ⅡC末端结构域抑制剂及其抗肿瘤活性
- 抗-HIV-1试剂
- 蛋白质与蛋白质的相互作用的抑制剂
- 羟色胺5-HT1A受体的部分激动剂
- 生长激素促分泌剂
- 血管内皮生长因子（VEGF）抑制剂
- A2B腺苷受体配体
- 十字花科植物抗毒素黄铜素的潜在解毒抑制剂
- 白细胞介素6抑制剂
- 双重结合位点乙酰胆碱酯酶抑制剂
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Ivan Kosalec et al.
Arhiv za higijenu rada i toksikologiju, 62(1), 41-49 (2011-03-23)
Tryptophol is an aromatic alcohol and secondary metabolite of the opportunistic fungus Candida albicans. Although its toxicity profile at cell level has been poorly investigated, recent data point to cytotoxic, cytostatic, and genotoxic effects in lymphocytes and the induction of
Chuan Liu et al.
Organic letters, 14(17), 4525-4527 (2012-08-16)
Copper(I)-catalyzed dearomative arylation and vinylation of 2-substituted tryptophols were realized with a subsequent cyclization reaction. The cascade dearomatization sequence provided versatile furoindoline derivatives with two quaternary carbon centers in good to excellent yields.
Richard Pozdrik et al.
Journal of agricultural and food chemistry, 54(17), 6123-6129 (2006-08-17)
The disappearance of riboflavin absorbance at 445 nm from beers or model beers on light exposure is directly linked to light-struck character formation. The addition of (+)-catechin, (-)-epicatechin, tryptophol, or ascorbic acid was able to reduce, but not stop, absorbance
Xuqing Zhang et al.
Organic letters, 7(10), 2043-2046 (2005-05-07)
The tetrahydro-pyrano[3,4-b]indoles 6 were synthesized from 2-(2-trimethylsilanyl-1H-indol-3-yl)-ethanols 5 and various ketones or aldehydes through silicon-directed oxa-Pictet-Spengler cyclizations. An unusual reaction led to the dimeric products 7 when some of 5 was treated with acetone using BF(3) as the catalyst.
Atiqur Rahman et al.
Bioscience, biotechnology, and biochemistry, 74(11), 2202-2208 (2010-11-13)
Rhizobacteria isolated from wild dipterocarp saplings in Central Kalimantan, Indonesia, were subjected to Salkowski's reagent test, which is often used in detecting indolic substances. Among 69 isolates grown in a low-nitrogen medium supplemented with L-tryptophan (TRP), culture fluids of 29
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