方案
97%
mp
56-59 °C (lit.)
SMILES字符串
OCCc1c[nH]c2ccccc12
InChI
1S/C10H11NO/c12-6-5-8-7-11-10-4-2-1-3-9(8)10/h1-4,7,11-12H,5-6H2
InChI key
MBBOMCVGYCRMEA-UHFFFAOYSA-N
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应用
作为反应物用于制备:
- RNA聚合酶ⅡC末端结构域抑制剂及其抗肿瘤活性
- 抗-HIV-1试剂
- 蛋白质与蛋白质的相互作用的抑制剂
- 羟色胺5-HT1A受体的部分激动剂
- 生长激素促分泌剂
- 血管内皮生长因子(VEGF)抑制剂
- A2B腺苷受体配体
- 十字花科植物抗毒素黄铜素的潜在解毒抑制剂
- 白细胞介素6抑制剂
- 双重结合位点乙酰胆碱酯酶抑制剂
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Alessandro Palmieri et al.
Organic & biomolecular chemistry, 10(17), 3486-3493 (2012-03-22)
Reduction of ketosulfonyl indoles with sodium borohydride provides a ready entry to tryptophols in a regiocomplementary fashion with respect to the traditional oxirane ring-opening by indoles under Friedel-Crafts conditions. Compared to traditional β-ketosulfones, ketosulfonyl indoles show a peculiar behavior since
Stefan Kehraus et al.
Journal of natural products, 65(7), 1056-1058 (2002-07-27)
Geometricin A (1), together with the known compounds (7E,12E,18S,20Z)-variabilin (2), clathryimine A (3), tryptophol (4), and L-tryptophan, has been isolated from the methanol extract of the Australian sponge Luffariella geometrica. The structure of the new compound geometricin A (1) was
B Adam Lenhart et al.
G3 (Bethesda, Md.), 9(5), 1533-1544 (2019-03-14)
In fungi, filamentous growth is a major developmental transition that occurs in response to environmental cues. In diploid Saccharomyces cerevisiae, it is known as pseudohyphal growth and presumed to be a foraging mechanism. Rather than unicellular growth, multicellular filaments composed
Hao Chen et al.
Genes & development, 20(9), 1150-1161 (2006-04-19)
Many fungi undergo a developmental transition from a unicellular yeast form to an invasive filamentous form in response to environmental cues. Here we describe a quorum signaling pathway that links environmental sensing to morphogenesis in Saccharomyces cerevisiae. Saccharomyces cells secrete
Dina Morshedi et al.
The FEBS journal, 274(24), 6415-6425 (2007-11-22)
Amyloid aggregation of polypeptides is related to a growing number of pathologic states known as amyloid disorders. There is a great deal of interest in developing small molecule inhibitors of the amyloidogenic processes. In the present article, the inhibitory effects
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