所有图片(2)

文件

T90301

3-(2-羟乙基)吲哚

Name: 3-(2-羟乙基)吲哚
Brand: ALDRICH

97%

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所有图片(2)

别名:

2-（3-吲哚基）乙醇, 3-吲哚乙醇, IEA, NSC 3884, 色醇

经验公式（希尔记法）:

C₁₀H₁₁NO

CAS号:

526-55-6

分子量:

161.20

Beilstein:

125553

EC 号:

208-393-2

MDL编号:

MFCD00005659

PubChem化学物质编号:

24900580

NACRES:

NA.22

检测方案

97%

mp

56-59 °C (lit.)

SMILES string

OCCc1c[nH]c2ccccc12

InChI

1S/C10H11NO/c12-6-5-8-7-11-10-4-2-1-3-9(8)10/h1-4,7,11-12H,5-6H2

InChI key

MBBOMCVGYCRMEA-UHFFFAOYSA-N

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应用

作为反应物用于制备：

RNA聚合酶ⅡC末端结构域抑制剂及其抗肿瘤活性
抗-HIV-1试剂
蛋白质与蛋白质的相互作用的抑制剂
羟色胺5-HT1A受体的部分激动剂
生长激素促分泌剂
血管内皮生长因子（VEGF）抑制剂
A2B腺苷受体配体
十字花科植物抗毒素黄铜素的潜在解毒抑制剂
白细胞介素6抑制剂
双重结合位点乙酰胆碱酯酶抑制剂

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Feedback control of morphogenesis in fungi by aromatic alcohols.

Hao Chen et al.

Genes & development, 20(9), 1150-1161 (2006-04-19)

Many fungi undergo a developmental transition from a unicellular yeast form to an invasive filamentous form in response to environmental cues. Here we describe a quorum signaling pathway that links environmental sensing to morphogenesis in Saccharomyces cerevisiae. Saccharomyces cells secrete

A new cytotoxic calyculinamide derivative, geometricin A, from the Australian sponge Luffariella geometrica.

Stefan Kehraus et al.

Journal of natural products, 65(7), 1056-1058 (2002-07-27)

Geometricin A (1), together with the known compounds (7E,12E,18S,20Z)-variabilin (2), clathryimine A (3), tryptophol (4), and L-tryptophan, has been isolated from the methanol extract of the Australian sponge Luffariella geometrica. The structure of the new compound geometricin A (1) was

Variation in Filamentous Growth and Response to Quorum-Sensing Compounds in Environmental Isolates of Saccharomyces cerevisiae.

B Adam Lenhart et al.

G3 (Bethesda, Md.), 9(5), 1533-1544 (2019-03-14)

In fungi, filamentous growth is a major developmental transition that occurs in response to environmental cues. In diploid Saccharomyces cerevisiae, it is known as pseudohyphal growth and presumed to be a foraging mechanism. Rather than unicellular growth, multicellular filaments composed

Ketosulfonyl indoles in the regiodefined synthesis of tryptophols and related indole derivatives.

Alessandro Palmieri et al.

Organic & biomolecular chemistry, 10(17), 3486-3493 (2012-03-22)

Reduction of ketosulfonyl indoles with sodium borohydride provides a ready entry to tryptophols in a regiocomplementary fashion with respect to the traditional oxirane ring-opening by indoles under Friedel-Crafts conditions. Compared to traditional β-ketosulfones, ketosulfonyl indoles show a peculiar behavior since

Trichoderma virens, a plant beneficial fungus, enhances biomass production and promotes lateral root growth through an auxin-dependent mechanism in Arabidopsis.

Hexon Angel Contreras-Cornejo et al.

Plant physiology, 149(3), 1579-1592 (2009-01-30)

Trichoderma species belong to a class of free-living fungi beneficial to plants that are common in the rhizosphere. We investigated the role of auxin in regulating the growth and development of Arabidopsis (Arabidopsis thaliana) seedlings in response to inoculation with

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