V2208
4-乙烯基-1-环己烯
99%
别名:
4-乙烯基-1-环己烯, 神经干细胞 15760
蒸汽密度
3.76 (vs air)
蒸汽压
10.2 mmHg ( 25 °C)
方案
99%
自燃温度
517 °F
包含
25-200 ppm p-tert-butylcatechol as inhibitor
折射率
n20/D 1.463 (lit.)
沸点
126-127 °C (lit.)
mp
−101 °C (lit.)
密度
0.831 g/mL at 20 °C
0.832 g/mL at 25 °C (lit.)
储存温度
2-8°C
SMILES字符串
C=CC1CCC=CC1
InChI
1S/C8H12/c1-2-8-6-4-3-5-7-8/h2-4,8H,1,5-7H2
InChI key
BBDKZWKEPDTENS-UHFFFAOYSA-N
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警示用语：
Danger
危险分类
Aquatic Chronic 3 - Asp. Tox. 1 - Carc. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
60.8 °F - closed cup
闪点(°C)
16 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
J K Doerr-Stevens et al.
Drug metabolism and disposition: the biological fate of chemicals, 27(2), 281-287 (1999-02-04)
4-Vinylcyclohexene (VCH), an ovarian toxicant in mice, is known to irreversibly deplete ovarian follicles as a consequence of VCH diepoxide formation. Because ovotoxicity requires repeated dosing of VCH, the effect of consecutive daily doses of VCH (7.5 mmol/kg/day) on mouse
Ellen A Cannady et al.
Toxicological sciences : an official journal of the Society of Toxicology, 68(1), 24-31 (2002-06-21)
Microsomal epoxide hydrolase (mEH) is involved in the detoxification of xenobiotics that are or can form epoxide metabolites, including the ovotoxicant, 4-vinylcyclohexene (VCH). This industrial chemical is bioactivated by hepatic CYP450 to the diepoxide metabolite, VCD, which destroys mouse small
P J Devine et al.
Frontiers in bioscience : a journal and virtual library, 7, d1979-d1989 (2002-08-06)
Many investigations have utilized techniques for culturing ovarian tissue or isolated follicles in vitro. Whole ovaries from fetal or neonatal rodents have been incubated in organ culture systems. This has been utilized to understand the sequence of follicle formation and
P B Hoyer et al.
Annual review of pharmacology and toxicology, 36, 307-331 (1996-01-01)
The ovary plays a pivotal role in the regulation of reproductive function in females. Development, maturation, and ovulation of oocytes occur within ovarian follicles. Females are born with a finite number of undeveloped, primordial follicles. Chemicals that destroy oocytes contained
S M Fontaine et al.
Life sciences, 69(8), 923-934 (2001-08-08)
4-Vinyl-1-cyclohexene (VCH), is converted by multiple forms of cytochrome P450 (CYP) to two monoepoxides (4-vinyl-1-cyclohexene 1,2-epoxide [VCH-1,2-epoxide], 4-vinyl-1-cyclohexene 7,8-epoxide [VCH-7,8-epoxide]), and 4-vinyl-1-cyclohexene diepoxide (VCD). A greater degree of formation of these epoxides by female B6C3F1 mice as compared to Fischer
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