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Merck
CN

W247006

乙酸异丁香酚酯

≥98%, FCC, FG

别名:

NSC 46121

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关于此项目

经验公式(希尔记法):
C12H14O3
化学文摘社编号:
分子量:
206.24
FEMA Number:
2470
Council of Europe no.:
220
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.030
EC Number:
202-236-1
NACRES:
NA.21
MDL number:
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产品名称

乙酸异丁香酚酯, ≥98%, FCC, FG

SMILES string

COc1cc(\C=C\C)ccc1OC(C)=O

InChI

1S/C12H14O3/c1-4-5-10-6-7-11(15-9(2)13)12(8-10)14-3/h4-8H,1-3H3/b5-4+

InChI key

IUSBVFZKQJGVEP-SNAWJCMRSA-N

biological source

synthetic

grade

FG
Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

assay

≥98%

composition

contains IFRA restricted Isoeugenol

mp

79-81 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

isoeugenol

organoleptic

carnation; floral; spicy; sweet

Quality Level

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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Suresh Chandra Rastogi et al.
Contact dermatitis, 58(5), 278-281 (2008-04-18)
Isoeugenol, an important fragrance allergen in consumers, has been restricted to 200 p.p.m. since 1998 according to guidelines issued by the fragrance industry. However, no decline in contact allergy to isoeugnol has been detected. It has been speculated that isoeugenol
I R White et al.
Contact dermatitis, 41(5), 272-275 (1999-12-20)
The prevalence of contact allergy to the fragrance mix in individuals with eczema is up to 10%. Within the mix, isoeugenol (CAS 97-54-1) is an important individual allergen. Until May 1998, the IFRA (International Fragrance Association) guidelines suggested that isoeugenol
R ten Have et al.
The Biochemical journal, 347(Pt 2), 585-591 (2000-04-06)
Lignin peroxidase (LiP) has been used to study the C(alpha)-C(beta) cleavage of the propylene side chain in 1-(3',4'-dimethoxyphenyl)propene (DMPP) to 3,4-dimethoxybenzaldehyde (veratraldehyde, VAD). Under an air atmosphere, LiP oxidized DMPP to VAD (27.8%) and 1-(3',4'-dimethoxyphenyl)propan-2-one (DMPA, 8.7%), after 10 min
Fragrance allergen substitution.
J Middleton
Contact dermatitis, 42(4), 249-249 (2000-04-06)
S Tanaka et al.
Contact dermatitis, 51(5-6), 288-291 (2004-12-21)
A total of 2261 (808 male, 1453 female) consecutive patients attending contact dermatitis clinics were patch tested to isoeugenol and its derivatives listed in the EU Inventory of Fragrance Ingredients. Positive reactions were found to isoeugenol in 40, transisoeugenol in

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