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Merck
CN

W271004

4-羟基苯甲酸甲酯

≥99%, FCC

别名:

对羟基苯甲酸甲酯, 对羟苯甲酸甲酯, 尼泊金甲酯

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关于此项目

线性分子式:
HOC6H4CO2CH3
化学文摘社编号:
分子量:
152.15
PubChem Substance ID:
UNSPSC Code:
12164502
Council of Europe no.:
657c
FEMA Number:
2710
NACRES:
NA.21
EC Number:
202-785-7
MDL number:
Beilstein/REAXYS Number:
509801
Organoleptic:
odorless
Grade:
Fragrance grade
Kosher
Biological source:
synthetic
Agency:
follows IFRA guidelines
Food allergen:
no known allergens
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产品名称

4-羟基苯甲酸甲酯, ≥99%, FCC

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

SMILES string

COC(=O)c1ccc(O)cc1

biological source

synthetic

grade

Fragrance grade
Kosher

agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
FCC
FDA 21 CFR 172.515

assay

≥99%

mp

125-128 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

odorless

Quality Level

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Disclaimer

仅供R&D或非EU食品使用不用于零售。

本品不可用作全球生物杀灭剂法规监管的生物杀灭剂,包括但不限于:美国联邦杀虫剂、杀菌剂和灭鼠剂法(US EPA′s Federal Insecticide Fungicide and Rodenticide Act)、欧盟生物杀灭剂法规(European Biocidal Products Regulation)、加拿大虫害管理监管机构(Canada’s Pest Management Regulatory Agency)、土耳其生物杀灭剂法规(Turkey’s Biocidal Products Regulation)、韩国生物杀灭剂法(Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR))等。

General description

4-羟基苯甲酸甲酯是食品、药品和化妆品中常用的抗菌防腐剂。它天然存在于 Securidaca longepedunculata Fers 根中。

pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Evaluation of the health aspects of methyl paraben: a review of the published literature.
Soni MG, et al.
Food And Chemical Toxicology, 40(10, 1335-1373 (2002)
Essential oils of Nigeria II: analysis of the leaf oil of Securidaca longependuculata Fers.
Adebayo MA, et al.
J. Essent. Oil Res., 19(5, 452-454 (2007)
Jia Chen et al.
Journal of chromatography. A, 1591, 33-43 (2019-01-21)
A novel supramolecular solvent (SUPRAS) based on hexafluoroisopropanol (HFIP)/Brij-35 was proposed for liquid-phase microextraction (LPME) of parabens in water samples, pharmaceuticals and personal care products. Brij-35 is a cost-effective and non-toxic non-ionic surfactant, but it has a high cloud point
Raena Morley et al.
Journal of chromatography. A, 1501, 26-38 (2017-05-05)
Trapping multiple dual mode centrifugal partition chromatography (trapping MDM CPC) is an alternative to isocratic pulse injections for the separation of intermediately-eluting components from complex mixtures using liquid-liquid chromatography. In this work, a throughput maximization strategy is developed and validated
Tony Hadibarata et al.
Journal of water and health, 18(1), 38-47 (2020-03-05)
The study was performed to examine the occurrence of endocrine disrupting chemicals (EDCs), including four steroid estrogens, one plasticizer, and three preservatives in the Mahakam River, Indonesia. The physicochemical analysis of river water and sediment quality parameters were determined as

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