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文件

W276405

Sigma-Aldrich

肉豆蔻酸

≥95%, FCC, FG

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别名:
1-十三烷羧酸, C14：0, NSC 5028, 十四烷酸
线性分子式:
CH3(CH2)12COOH
CAS号:
544-63-8
分子量:
228.37
FEMA编号:
2764
Beilstein:
508624
EC 号:
208-875-2
欧洲委员会编号:
16
MDL编号:
MFCD00002744
PubChem化学物质编号:
24901313
Flavis编号:
8.016
NACRES:
NA.21

生物来源

synthetic

质量水平

400

等级

FG
Fragrance grade
Halal
Kosher

Agency

follows IFRA guidelines
meets purity specifications of JECFA

管理合规性

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 172.210
FDA 21 CFR 172.860
FDA 21 CFR 173.340

检测方案

≥95%

bp

250 °C/100 mmHg (lit.)

mp

52-54 °C (lit.)

应用

flavors and fragrances

文件

see Safety & Documentation for available documents

食品过敏原

no known allergens

致敏芳香化合物

no known allergens

性状检查

oily; waxy; soapy

SMILES字符串

CCCCCCCCCCCCCC(O)=O

InChI

1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)

InChI key

TUNFSRHWOTWDNC-UHFFFAOYSA-N

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相关类别

生化/生理作用

肉豆蔻酸通常通过共价键添加到许多真核和病毒蛋白的N-末端甘氨酸中，该过程称为肉豆蔻酰化。肉豆蔻酰化使蛋白质与细胞膜结合，并促进蛋白质与蛋白质相互作用。蛋白质的肉豆蔻酸化影响许多细胞功能，因而对健康和疾病有影响。

免责声明

The substance W276405 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

储存分类代码

11 - Combustible Solids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Sheen X Lu et al.
Plant molecular biology, 82(3), 267-278 (2013-04-24)
Calcium-dependent protein kinases (CDPK) are a major group of calcium-stimulated kinases found in plants and some protists. Many CDPKs are membrane-associated, presumably because of lipid modifications at their amino termini. We investigated the subcellular location and myristoylation of AtCPK5, a
Dalit Shental-Bechor et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(44), 17839-17844 (2012-08-01)
We present an integrated experimental and computational study of the molecular mechanisms by which myristoylation affects protein folding and function, which has been little characterized to date. Myristoylation, the covalent linkage of a hydrophobic C14 fatty acyl chain to the
Anja Meier et al.
Hepatology (Baltimore, Md.), 58(1), 31-42 (2012-12-06)
Chronic infection with the human hepatitis B virus (HBV) is a global health problem and a main cause of progressive liver diseases. HBV exhibits a narrow host range, replicating primarily in hepatocytes. Both host and hepatocyte specificity presumably involve specific
S Curry et al.
Biochimica et biophysica acta, 1441(2-3), 131-140 (1999-11-26)
Human serum albumin possesses multiple fatty acid binding sites of varying affinities, but the precise locations of these sites have remained elusive. The determination of the crystal structure of human serum albumin complexed with myristic acid recently revealed the positions
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The Journal of clinical investigation, 122(11), 3919-3930 (2012-10-02)
Diabetic cardiomyopathy (DbCM), which consists of cardiac hypertrophy and failure in the absence of traditional risk factors, is a major contributor to increased heart failure risk in type 2 diabetes patients. In rodent models of DbCM, cardiac hypertrophy and dysfunction
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