W290904
胡椒碱
≥95%, FG
别名:
1-胡椒酰哌啶
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关于此项目
经验公式（希尔记法）:
C17H19NO3
化学文摘社编号:
分子量:
285.34
FEMA Number:
2909
Council of Europe no.:
492
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
14.003
EC Number:
202-348-0
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
90741
Organoleptic:
fatty; pepper
Grade:
FG
Halal
Kosher
Halal
Kosher
Biological source:
Piper nigrum L.
Food allergen:
no known allergens
产品名称
胡椒碱, ≥95%, FG
SMILES string
O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
InChI
1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChI key
MXXWOMGUGJBKIW-YPCIICBESA-N
biological source
Piper nigrum L.
grade
FG
Halal
Kosher
reg. compliance
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 172.515
assay
≥95%
form
powder, crystals or granules
mp
131-135 °C (lit.)
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
organoleptic
fatty; pepper
Gene Information
human ... CYP3A4(1576)
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Biochem/physiol Actions
Piperine, a major component of black pepper extracts, shown to have potential for inhibiting fat cell formation.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
Ui-Hyun Park et al.
Journal of agricultural and food chemistry, 60(15), 3853-3860 (2012-04-03)
This study investigated the antiadipogenic activity of black pepper extract and its constituent piperine in 3T3-L1 preadipocytes as well as the underlying molecular mechanisms. Both black pepper extract and piperine, without affecting cytotoxicity, strongly inhibited the adipocyte differentiation of 3T3-L1
Janine Zaugg et al.
Journal of natural products, 73(2), 185-191 (2010-01-21)
A plant extract library was screened for GABA(A) receptor activity making use of a two-microelectrode voltage clamp assay on Xenopus laevis oocytes. An ethyl acetate extract of black pepper fruits [Piper nigrum L. (Piperaceae) 100 microg/mL] potentiated GABA-induced chloride currents
Clara Grosso et al.
Phytochemical analysis : PCA, 24(2), 141-147 (2012-09-19)
Depression is a mental disease causing large personal and socio-economic problems, and new improved drugs are therefore needed. Selective monoamine oxidase A (MAO-A) inhibitors are potential anti-depressants, but discovering new MAO-A inhibitors from natural sources by bioassay-guided approaches are a
Hyung Gyun Kim et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(7), 2342-2348 (2012-05-01)
Piperine is a major component of black (Piper nigrum Linn) and long (Piper longum Linn) peppers, and is widely used as a traditional food and medicine. It also exhibits a variety of biological activities, which include antioxidant, anti-tumor and anti-pyretic
Paul B Yaffe et al.
Experimental and molecular pathology, 94(1), 109-114 (2012-10-16)
Piperine, an alkaloid phytochemical found in the fruit of black and long pepper plants, is reported to inhibit the growth of cancer cells; however, the mechanism of action in human cancer cells is not clear. In this study we investigated
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