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Merck
CN

W304409

L-(+)-酒石酸

≥99.7%, FCC, FG

别名:

(2R,3R)-(+)-酒石酸, 左旋酒石酸

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线性分子式:
HO2CCH(OH)CH(OH)CO2H
化学文摘社编号:
87-69-4
分子量:
150.09
FEMA Number:
3044
Council of Europe no.:
18
UNSPSC Code:
12164502
PubChem Substance ID:
24901442
NACRES:
NA.21
EC Number:
201-766-0
Flavis number:
8.018
MDL number:
MFCD00064207
Beilstein/REAXYS Number:
1725147
Organoleptic:
odorless
Grade:
FG, Halal
Biological source:
synthetic
Agency:
meets purity specifications of JECFA
Food allergen:
no known allergens

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SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O

InChI

1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2-/m1/s1

InChI key

FEWJPZIEWOKRBE-JCYAYHJZSA-N

biological source

synthetic

grade

FG, Halal

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 178/2002, FCC, FDA 21 CFR 163.110, FDA 21 CFR 163.111, FDA 21 CFR 163.112, FDA 21 CFR 184.1099

vapor density

5.18 (vs air)

assay

≥99.7%

form

crystalline powder

optical activity

[α]20/D +12.5°, c = 20 in H2O

autoignition temp.

797 °F

mp

170-172 °C (lit.)

solubility

water: soluble 150 g/L at 25 °C

cation traces

As: ≤3 ppm, Cd: ≤1 ppm, Hg: ≤1 ppm, heavy metals (as Pb): ≤2 ppm

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

Quality Level

300, 400

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相关类别

General description

L -(+)-酒石酸是一种有机酸，常用作酸剂、增味剂、固化剂和湿润剂。

Application


  • 太赫兹光谱法无损测定smartFilm和纸型片剂中L-酒石酸的结晶度。：本研究采用太赫兹光谱法评估创新制药应用中L-(+)-酒石酸的结晶度，改善了质量控制的无损检测方法（Ornik et al., 2020 May）。文章链接。

  • 微粉化共晶干粉制剂改善难溶性伊曲康唑的肺部吸收。研究表明，在伊曲康唑的共晶制剂中使用L-(+)-酒石酸可改善其肺部吸收，这表明药物递送技术取得了重大进展（Karashima et al., 2017 Jun）。文章链接。

  • 低溶性药物共无定形体的理化评价和可开发性评估以及与共晶体的比较。：本文讨论了L-(+)-酒石酸通过共无定形体系提高药物溶解度和生物利用度的作用，为药物制剂策略提供了重要见解（Yamamoto et al., 2016 Dec）。文章链接。

  • 源自酒石酸的功能化聚碳酸酯：七元环状碳酸酯的酶促开环聚合。：本研究探讨了由L-(+)-酒石酸合成可生物降解聚合物，强调了其在开发环保材料方面的应用（Wu et al., 2008 Oct）。文章链接。

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

存储类别

11 - Combustible Solids

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SHBT5006
SHBR4882
SHBQ3265
SHBP4508
SHBN6790

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Dictionary of Food Compounds with CD-ROM: Additives, Flavors, and Ingredients, 1794-1794 (2012)
J B Olivato et al.
Carbohydrate polymers, 92(2), 1705-1710 (2013-02-13)
Tartaric acid (TA), a dicarboxylic acid, can act as a compatibiliser in starch/polyester blends. A mixture design was proposed to evaluate the effect of TA on the properties of starch/poly (butylene adipate co-terephthalate) (PBAT) blown films plasticised with glycerol. The
Mrinal Kanti Bain et al.
Carbohydrate polymers, 91(2), 529-536 (2012-11-06)
Gelation temperature of MC was reduced from 59°C to 54°C with the addition of 10% PEG. Sodium tartrate (NaT) and sodium citrate (NaC) were added to the MC-PEG solution to further reduce the gelation temperature close to physiological temperature. Different
Mark D Eddleston et al.
Chemical communications (Cambridge, England), 48(92), 11340-11342 (2012-10-18)
The formation of diastereomeric cocrystals of malic acid and tartaric acid was investigated by liquid-assisted grinding in the solid state. We demonstrate that racemic malic acid can be converted into two distinct diastereomeric cocrystal phases by grinding with a single
Andrea Bencini et al.
Chemical communications (Cambridge, England), 48(84), 10428-10430 (2012-09-18)
A chiral ditopic polyammonium receptor featuring two [9]aneN(3) moieties separated by a (S)-BINOL linker is able to selectively bind and sense in water (S,S)-tartaric acid over its (R,R)/meso forms.
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