W329118

4-羟基丁酸内酯

Name: 4-羟基丁酸内酯
Brand: ALDRICH

≥98%, FCC, FG

别名:

γ-丁内酯, γ-羟基丁酸内酯, 4-羟基丁酸内酯, GBL

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经验公式（希尔记法）:

C₄H₆O₂

化学文摘社编号:

96-48-0

分子量:

86.09

FEMA Number:

3291

Council of Europe no.:

615

UNSPSC Code:

12164502

PubChem Substance ID:

24901615

Flavis number:

10.006

EC Number:

202-509-5

NACRES:

NA.21

MDL number:

MFCD00005386

Beilstein/REAXYS Number:

105248

Organoleptic:

caramel; creamy; fatty; oily

Grade:

FG
Fragrance grade
Halal
Kosher

Biological source:

synthetic

Agency:

follows IFRA guidelines
meets purity specifications of JECFA

Food allergen:

no known allergens

主要文件

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产品名称

4-羟基丁酸内酯, ≥98%, FCC, FG

SMILES string

O=C1CCCO1

InChI

1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2

InChI key

YEJRWHAVMIAJKC-UHFFFAOYSA-N

biological source

synthetic

grade

FG
Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines
meets purity specifications of JECFA

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA

vapor density

3 (vs air)

vapor pressure

1.5 mmHg ( 20 °C)

assay

≥98%

autoignition temp.

851 °F

expl. lim.

16 %

drug control

Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

refractive index

n20/D 1.436 (lit.)

bp

204-205 °C (lit.)

mp

−45 °C (lit.)

density

1.12 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

caramel; creamy; fatty; oily

Quality Level

300
400

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Biochem/physiol Actions

γ-羟基丁酸(GHB)前体。可通过阻断多巴胺能神经元的脉冲流，抑制多巴胺释放。 γ-丁内酯预处理可用于检测自身受体诱导的多巴胺释放。

γ-羟基丁酸(GHB)前体；抑制多巴胺释放。

Application

RIFM fragrance ingredient safety assessment, 4-hydroxybutanoic acid lactone, CAS Registry Number 96-48-0.: A comprehensive safety assessment of 4-hydroxybutanoic acid lactone as a fragrance ingredient, evaluating its toxicological profile and safe usage levels (Api et al., 2019).

pictograms

GHS05,GHS07

signalword

Danger

hcodes

H302,H318,H336

pcodes

P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

target_organs

Central nervous system

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

208.4 °F - closed cup

flash_point_c

98 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

易制毒化学品（3类）

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The GIRK2 subunit is involved in IS-like seizures induced by GABA(B) receptor agonists.

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Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation.

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4-羟基丁酸内酯

≥98%, FCC, FG

选择尺寸

关于此项目

主要文件

属性

产品名称

SMILES string

InChI

InChI key

biological source

grade

agency

reg. compliance

vapor density

vapor pressure

assay

autoignition temp.

expl. lim.

drug control

refractive index

bp

mp

density

application(s)

documentation

food allergen

fragrance allergen

organoleptic

Quality Level

相关类别

说明

Biochem/physiol Actions

Application

安全信息

pictograms

signalword

hcodes

pcodes

Hazard Classifications

target_organs

存储类别

wgk

flash_point_f

flash_point_c

ppe

法规信息

文件

分析证书(COA)

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