W332208
硫胺 盐酸盐
≥98%, FCC, FG
别名:
硫胺素 盐酸盐, 维生素 B 1 盐酸盐
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关于此项目
经验公式（希尔记法）:
C12H17ClN4OS · HCl
CAS Number:
分子量:
337.27
FEMA编号:
3322
Beilstein:
3851771
EC 号:
欧洲委员会编号:
4226
MDL编号:
UNSPSC代码:
12164502
PubChem化学物质编号:
Flavis编号:
16.027
NACRES:
NA.21
Agency:
meets purity specifications of JECFA
生物来源
synthetic
等级
FG
Halal
Kosher
Agency
meets purity specifications of JECFA
管理合规性
EU Regulation 1334/2008 & 872/2012
FCC
方案
≥98%
表单
powder or crystals
颜色
white to yellow-white
mp
250 °C (dec.) (lit.)
溶解性
H2O: 1 g/10 mL, clear, colorless
应用
flavors and fragrances
文件
see Safety & Documentation for available documents
食品过敏原
no known allergens
性状检查
sour
SMILES字符串
CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
InChI
1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
InChI key
DPJRMOMPQZCRJU-UHFFFAOYSA-M
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一般描述
Thiamine hydrochloride is a water-soluble vitamin generally used as a nutrient supplement. When it undergoes heat-degradation, it may form volatile flavor compounds such as hydrogen sulfide, 2-methylthiopehene, 2-methylfuran, and 4,5-dihydro-2-methylthiophene.
应用
- Construction of hyaluronic acid-functionalized magnolol nanoparticles for ulcerative colitis treatment.: This innovative study explores the synthesis of nanoparticle systems using hyaluronic acid-functionalized magnolol, highlighting thiamine hydrochloride′s role in enhancing therapeutic efficacy and stability in gastrointestinal treatments. This research underlines the biochemical application of thiamine hydrochloride in developing advanced drug delivery systems (Li Y et al., 2024).
- Constructing Highly Stable Zinc Metal Anodes via Induced Zn(002) Growth.: Investigates the electrochemical stability of zinc anodes, with thiamine hydrochloride playing a critical role in modulating the electrochemical properties and enhancing the anode′s performance, showcasing its potential in next-generation battery technologies (Hu S et al., 2024).
- Subclinical thiamine deficiency results in failed reproduction in Arctic foxes.: This study identifies the pivotal role of thiamine hydrochloride in preventing reproductive failures linked to nutritional deficiencies in wildlife, extending its application beyond human health to include environmental and conservation aspects (Jackson C et al., 2024).
- Density Functional Theory and Density Functional Tight Binding Studies of Thiamine Hydrochloride Hydrates.: Highlights computational studies on the molecular structure and stability of thiamine hydrochloride, providing crucial insights into its physicochemical properties and interactions at the molecular level, critical for pharmaceutical formulations (Napiórkowska E et al., 2023).
- Effects of Nutrients on the Growth of and Free Exopolysaccharide Biosynthesis by Streptococcus thermophilus 937 in a Chemically Defined Medium.: Examines the influence of thiamine hydrochloride among other nutrients on the microbial synthesis processes, underlining its essential role in microbial nutrition and metabolic engineering (Wa Y et al., 2023).
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Spectrophotometric determination of ascorbic acid and thiamine hydrochloride in pharmaceutical products using derivative spectrophotometry
Abdel-Hamid ME, et al.
Analyst, 110(7), 831-835 (1985)
Validation of HPLC method for determination of thiamine hydrochloride, riboflavin, nicotinamide, and pyridoxine hydrochloride in syrup preparation
Yantih N, et al.
Canadian Journal on Scientific and Industrial Research, 2(7), 269-278 (2011)
Encyclopedia of Food and Color Additives, 1, 2777-2777 null
Volatile flavor compounds produced by heat degradation of thiamine (vitamin B1).
Arnold RG, et al.
Journal of Agricultural and Food Chemistry, 17(2), 390-392 (1969)
Joseph E Kerschner et al.
Archives of otolaryngology--head & neck surgery, 135(1), 33-39 (2009-01-21)
To investigate genetic differences in middle ear mucosa (MEM) with nontypeable Haemophilus influenzae (NTHi) infection. Genetic upregulation and downregulation occurs in MEM during otitis media (OM) pathogenesis. A comprehensive assessment of these genetic differences using the techniques of complementary DNA
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