W355690
肉豆蔻酸异丙酯
≥98%
别名:
十四碳酸异丙酯, 十四酸异丙酯
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关于此项目
线性分子式:
CH3(CH2)12COOCH(CH3)2
化学文摘社编号:
分子量:
270.45
FEMA Number:
3556
Council of Europe no.:
386
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.105
EC Number:
203-751-4
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
1781127
Organoleptic:
faint; fatty; oily
Grade:
Fragrance grade
Halal
Kosher
Halal
Kosher
Biological source:
synthetic
Agency:
follows IFRA guidelines
Food allergen:
no known allergens
产品名称
肉豆蔻酸异丙酯, ≥98%
SMILES string
CCCCCCCCCCCCCC(=O)OC(C)C
InChI
1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI key
AXISYYRBXTVTFY-UHFFFAOYSA-N
biological source
synthetic
grade
Fragrance grade
Halal
Kosher
agency
follows IFRA guidelines
reg. compliance
EU Regulation 1223/2009
assay
≥98%
refractive index
n20/D 1.434 (lit.)
bp
193 °C/20 mmHg (lit.)
mp
~3 °C (lit.)
density
0.85 g/mL at 25 °C (lit.)
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
fragrance allergen
no known allergens
organoleptic
faint; fatty; oily
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Application
- 负载富含黄酮类化合物的姜属植物纳米结构脂质载体的开发：本研究开发了用于从姜黄中提取的黄酮类化合物的纳米结构脂质载体，利用肉豆蔻酸异丙酯稳定这些载体并改善生物活性化合物的递送。（Shazwani SS 等人，2024 年）
- 利格列汀经皮递送物理和化学增强技术的比较评估：该研究比较了多种用于经皮药物递送的增强方法，包括使用异丙基肉豆蔻酸酯，突出了其在渗透增强技术中的有效性。（Karve T 等人，2024 年）
- 利用响应面法优化花椒酰胺脂质体条件及其在 Caco-2 细胞单层模型中的吸收特性：本研究优化了含有花椒酰胺的脂质体配方，其中肉豆蔻酸异丙酯在脂质体稳定性和吸收特性中至关重要。（Wang R 等人，2024 年）
Biochem/physiol Actions
1.0% 时的气味
10ppm 时的味道
Disclaimer
仅供R&D或非EU食品使用不用于零售。
General description
肉豆蔻酸异丙酯主要用作化妆品和外用药物的增溶剂、乳化剂和润肤剂。它还被用作食品工业中的调味剂。
存储类别
10 - Combustible liquids
wgk
awg
flash_point_f
>302.0 °F
flash_point_c
> 150 °C
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Handbook of Preservatives, 425-425 (2004)
Ranajay Saha et al.
Langmuir : the ACS journal of surfaces and colloids, 28(22), 8309-8317 (2012-05-11)
An edible microemulsion (ME) composed of Tween 80/butyl lactate/isopropyl myristate (IPM)/water has been formulated. Pseudoternary phase diagram of the system contains a large single isotropic region. The phase behavior of the system is also studied at low pH (2.6) and
Fan Yang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 158-163 (2012-06-21)
Transdermal delivery of methotrexate (MTX) was investigated by using the solid-in-oil (S/O) technique. Because MTX was coated with nonionic surfactant molecules, the resulting complex was easy to dissolve in various organic solvents and provided a transparent solution in isopropyl myristate
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qian Zhang et al.
Pharmaceutical research, 30(1), 32-40 (2012-08-28)
In principle, maximum transepidermal fluxes of solutes should be similar for different vehicles, except when the solute or vehicle modifies the skin. Here we estimated maximum flux, stratum corneum solubility, diffusivity and permeability coefficient for a range of similarly sized
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