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Merck
CN

W379301

D-(-)-核糖

≥98%

别名:

D-核糖

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关于此项目

经验公式(希尔记法):
C5H10O5
化学文摘社编号:
分子量:
150.13
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352201
FEMA Number:
3793
EC Number:
200-059-4
MDL number:
Beilstein/REAXYS Number:
1723081
Organoleptic:
odorless
Biological source:
synthetic
Food allergen:
no known allergens
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产品名称

D-(-)-核糖, ≥98%

InChI key

PYMYPHUHKUWMLA-LMVFSUKVSA-N

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@@H](O)C([H])=O

biological source

synthetic

reg. compliance

FDA 21 CFR 117

assay

≥98%

optical activity

[α]21/D −19.7°, c = 4 in H2O

mp

88-92 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

Quality Level

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Application

  • 百里醌对d-核糖诱导的人肌红蛋白糖基化的保护作用。:本研究调查了百里醌对d-核糖诱导的人肌红蛋白糖基化的保护作用,重点介绍了其在预防蛋白质糖基化方面的潜在治疗应用(Liu et al., 2023)。

Disclaimer

用于研发&或非欧盟(EU)食品用途。不用于零售。

General description

D-(−)-核糖已在体外研究中研究了非酶促核糖在修饰骨胶原蛋白导致骨脆性中的作用。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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D-ribose and deoxy-D-ribose induce apoptosis in human quiescent peripheral blood mononuclear cells.
Barbieri D, et al.
Biochemical and Biophysical Research Communications, 201(3), 1109-1116 (1994)
Alice Pavlowsky et al.
Current biology : CB, 28(11), 1783-1793 (2018-05-22)
Memory consolidation is a crucial step for long-term memory (LTM) storage. However, we still lack a clear picture of how memory consolidation is regulated at the neuronal circuit level. Here, we took advantage of the well-described anatomy of the Drosophila
Xiang-Guo Li et al.
Chemical communications (Cambridge, England), 49(35), 3682-3684 (2013-03-29)
Peptide glycosylation with 5-deoxy-5-[(18)F]fluororibose was translated into preclinical settings. The novel (18)F-labeled Siglec-9 peptide was produced using an automated synthesis procedure. The (18)F-labeled Siglec-9 peptide showed favorable binding in the animal model of inflammation in vivo.
Carine Baraguey et al.
Organic & biomolecular chemistry, 11(16), 2638-2647 (2013-03-05)
The pivaloyloxymethyl (PivOM) group is a biolabile 2'-O-ribose protection that is under development in a prodrug-based approach for siRNA applications. Besides an expected cellular uptake, nucleic acid sequences carrying PivOM showed also increased nuclease resistance and, in most cases, an
Anders Virtanen et al.
Critical reviews in biochemistry and molecular biology, 48(2), 192-209 (2013-03-19)
Deadenylation of eukaryotic mRNA is a mechanism critical for mRNA function by influencing mRNA turnover and efficiency of protein synthesis. Here, we review poly(A)-specific ribonuclease (PARN), which is one of the biochemically best characterized deadenylases. PARN is unique among the

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