W421501
酪胺
98%, FG
别名:
2-(4-羟基苯基)乙胺, 4-(2-氨乙基)苯酚, 4-羟基苯乙胺
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关于此项目
线性分子式:
HOC6H4CH2CH2NH2
化学文摘社编号:
分子量:
137.18
Flavis number:
11.007
PubChem Substance ID:
UNSPSC Code:
12164502
FEMA Number:
4215
NACRES:
NA.21
EC Number:
200-115-8
MDL number:
Beilstein/REAXYS Number:
1099914
Organoleptic:
meaty; phenolic
Grade:
FG
Biological source:
synthetic
Food allergen:
no known allergens
产品名称
酪胺, 98%, FG
InChI
1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2
SMILES string
NCCc1ccc(O)cc1
InChI key
DZGWFCGJZKJUFP-UHFFFAOYSA-N
biological source
synthetic
grade
FG
reg. compliance
EU Regulation 1334/2008 & 872/2012
FDA 21 CFR 110
assay
98%
bp
175-181 °C/8 mmHg (lit.)
mp
160-162 °C (lit.)
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
organoleptic
meaty; phenolic
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Biochem/physiol Actions
可以进入儿茶酚胺能末梢并作为伪递质释放。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Giris Jacob et al.
Circulation, 107(19), 2475-2479 (2003-04-23)
Despite the widespread use of tyramine as a pharmacological tool to assess the effects of norepinephrine release from sympathetic nerve terminals, its vascular effects are not adequately characterized. In particular, previous results indicate that intravenous tyramine produces little if any
Stephan A Chalon et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 28(9), 1685-1693 (2003-06-05)
Evidence suggests that compounds that increase the synaptic availability of more than one neurotransmitter have greater efficacy in the treatment of depression than single-acting drugs. Preclinical studies indicate that duloxetine acts to inhibit serotonin (5-HT) and norepinephrine (NE) transporters. The
Tony Huynh et al.
The Journal of pathology, 231(2), 223-235 (2013-06-25)
The over-expression of NF-κB signalling in both muscle and immune cells contribute to the pathology in dystrophic muscle. The anti-inflammatory properties of glucocorticoids, mediated predominantly through monomeric glucocorticoid receptor inhibition of transcription factors such as NF-κB (transrepression), are postulated to
D R Varma et al.
The Journal of pharmacology and experimental therapeutics, 265(3), 1096-1104 (1993-06-01)
At concentrations higher than that required to produce maximal vasoconstriction, tyramine caused concentration-dependent relaxation of rat aortic strips contracted maximally by tyramine, norepinephrine, phenylephrine, 5-hydroxytryptamine, prostaglandin F2 alpha, endothelin, angiotensin II and potassium; isoproterenol did not relax potassium-contracted strips. The
Thomas Roeder
Annual review of entomology, 50, 447-477 (2004-09-10)
Octopamine (OA) and tyramine (TA) are the invertebrate counterparts of the vertebrate adrenergic transmitters. They are decarboxylation products of the amino acid tyrosine, with TA as the biological precursor of OA. Nevertheless, both compounds are independent neurotransmitters that act through
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