Merck
CN

131601C

Avanti

Egg PC (95%)

Avanti Polar Lipids

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别名:
L-α-phosphatidylcholine (95%) (Egg, Chicken)
CAS号:
NACRES:
NA.25

检测方案

>99% (TLC)

形式

chloroform solution

包装

pkg of 2 × 20 mL (131601C-1g)

manufacturer/tradename

Avanti Polar Lipids

浓度

25 mg/mL (131601C-1g)

lipid type

phosphoglycerides
phospholipids

运输

dry ice

储存温度

−20°C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

一般描述

Egg L-α-phosphatidylcholine (PC) has palmitic acid (16:0) and oleic acid (18:1) at sn-1 and sn-2 positions, respectively. It constitutes 20% of the total phospholipids in egg.
Egg PC (95%) is a mixture of 16 to 22 carbon atoms long acyl chain containing multiple double bonds. Major portion (98%) of phospholipid contains a single saturated and unsaturated chain.
Egg PC is a further purification of Total Egg Extract. This Natural Lipid is a mixture, and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.

应用

Egg PC (95%) has been used for the reconstitution of nhTMEM16 into liposomes.
Egg PC (95%) is suitable for the preparation of multi-lamellar liposomes.
Egg PC (95%) is suitable for use in the liposome preparation for the reconstitution of lipid-linked oligosaccharide (LLO) flippase protein, Protein glyocyslaion K (PglK).

生化/生理作用

Egg L-α-phosphatidylcholine (PC) is used in lipid preparation and liposomes for biophysical studies. It serves as a substrate for microbes for trimethylamine N-oxide (TMAO) synthesis. Egg PC is used as a marker to access cardiovascular disease (CVD) risk.

包装

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (131601C-1g)

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品(2类)
危险化学品

分析证书(COA)

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示例

T1503
货号
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包装规格/数量

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1000309185

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索取COA

Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation
Perez C, et al.
Structure, 27(4), 669-678 (2019)
Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM
Kalienkova V, et al.
eLife, 8, e44364-e44364 (2019)
Characterization of interactions of eggPC lipid structures with different biomolecules
Chahar FC, et al.
Chemistry and Physics of Lipids, 210, 60-69 (2018)
Effects of Cholesterol Concentrations on Egg-phosphatidylcholine-Dihexadecyl-phosphate Liposomes Studied by CW ESR and FT-ESEEM Spectroscopy
Mirosavljevic K and Noethig-Laslo V
Croatica Chemica Acta. Arhiv Za Kemiju, 81(4), 631-636 (2008)
Egg phospholipids and cardiovascular health
Blesso C
Nutrients, 7(4), 2731-2747 (2015)

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