InChI
1S/C7H9N3O.BrH/c8-9-7(11)6-10-4-2-1-3-5-10;/h1-5H,6,8H2;1H/i1D,2D,3D,4D,5D;
InChI key
URTAUWVMJKDFIX-GWVWGMRQSA-N
SMILES string
O=C(NN)C[N+]1=C([2H])C([2H])=C([2H])C([2H])=C1[2H].[Br-]
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (640008P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Girard Reagents are N-substituted glycine hydrazides. They are classified as Girard-T (trimethylacetylhydrazide ammonium chloride), Girard-P (pyridinioacetohydrazide chloride) and Girard-D (N,N-dimethylglycine hydrazide hydrochloride). Girard Reagent-d5 is an isotope containing labeling reagent.
Biochem/physiol Actions
Girard reagents generate water-soluble hydrazones of carbonyl compounds aiding their separation. These reagents are sensitive and selective. d5-Girard reagent P (d5-GP) is useful in the labeling of steroid hormones for mass spectroscopy analysis enabling accurate cum sensitive steroid hormone quantification.
Packaging
5 mL Amber Glass Screw Cap Vial (640008P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Ning Guo et al.
Analytica chimica acta, 905, 106-114 (2016-01-13)
Steroid hormones play important roles in mammal at very low concentrations and are associated with numerous endocrinology and oncology diseases. Therefore, quantitative analysis of steroid hormones can provide crucial information for uncovering underlying mechanisms of steroid hormones related diseases. In
Transition metal complexes with Girard reagents and their hydrazones
Vojinovic-Jevsic LS, et al.
J. Serb. Chem. Soc., 77(9), 1129-1155 (2012)
Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols
Roberg-Larsen H, et al.
Journal of Lipid Research, 55(7), 1531-1536 (2014)
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