产品名称
胆固醇硫酸盐, Avanti Research™ - A Croda Brand 700016P
SMILES string
[Na+].[S](=O)(=O)([O-])O[C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CCCC(C)C)C)(CC3)C)CC=C2C1)C
InChI
1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1
InChI key
LMPVQXVJTZWENW-KPNWGBFJSA-M
description
cholesterol 3-sulfate (sodium salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 g (700016P-1g)
pkg of 1 × 25 mg (700016P-25mg)
pkg of 1 × 500 mg (700016P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700016P
shipped in
dry ice
storage temp.
−20°C
Application
胆固醇硫酸酯已被用于制备胶束以及表面等离子体共振（SPR）研究。
Biochem/physiol Actions
胆固醇硫酸酯与动脉粥样硬化病变有关，可作为血小板粘附的一种基质。它可稳定精子膜和红细胞。胆固醇硫酸酯可参与到角质细胞的分化，并在隐性X连锁鱼鳞病中水平上升。它可作为视黄酸相关孤儿受体α（RORα）的一种配体。胆固醇硫酸酯可调节葡萄糖代谢，是代谢紊乱的一个潜在靶点。它还是人类宫颈癌组织和前列腺癌的一种潜在标志物。
General description
胆固醇硫酸酯是在胆固醇硫转移酶存在下，由胆固醇的硫酸结合作用而合成的。它可存在于大脑、肺、头发和皮肤组织以及红细胞、血小板和精子等细胞中。
Packaging
20 mL 透明玻璃螺旋盖小瓶（700016P-1g）
20 mL 透明玻璃螺旋盖小瓶（700016P-500mg）
5 mL 琥珀色玻璃螺旋盖小瓶 (700016P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
M Merten et al.
Circulation, 103(16), 2032-2034 (2001-04-25)
Cholesterol 3-sulfate is present on a variety of cells and in human LDL, and it has been found in atherosclerotic lesions of human aorta. Its precise biological role has not yet been described. In this study, we investigated the interaction
Charles A Strott et al.
Journal of lipid research, 44(7), 1268-1278 (2003-05-06)
Cholesterol sulfate is quantitatively the most important known sterol sulfate in human plasma, where it is present in a concentration that overlaps that of the other abundant circulating steroid sulfate, dehydroepiandrosterone (DHEA) sulfate. Although these sulfolipids have similar production and
Alexey V Kostarnoy et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(13), E2758-E2765 (2017-03-16)
Sterile (noninfected) inflammation underlies the pathogenesis of many widespread diseases, such as allergies and autoimmune diseases. The evolutionarily conserved innate immune system is considered to play a key role in tissue injury recognition and the subsequent development of sterile inflammation;
Patrizia Lopalco et al.
Frontiers in physiology, 10, 1344-1344 (2019-11-19)
The reduction of sperm motility and count, or oligoasthenozoospermia, is one of the major causes of reduced fertility or infertility in men. Lipid composition of spermatozoa is important in determining their functional characteristics, in particular on motility, acrosomal exocytosis or
Xiongjie Shi et al.
Molecular and cellular biology, 34(3), 485-497 (2013-11-28)
Sulfotransferase (SULT)-mediated sulfation represents a critical mechanism in regulating the chemical and functional homeostasis of endogenous and exogenous molecules. The cholesterol sulfotransferase SULT2B1b catalyzes the sulfoconjugation of cholesterol to synthesize cholesterol sulfate (CS). In this study, we showed that the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持