描述
cholest-5-ene-3β,22(R)-diol-d7
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (700052P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
应用
lipidomics
metabolomics
运输
dry ice
储存温度
−20°C
一般描述
22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol. It is present in the neonate brain. 22(R)-hydroxycholesterol-d7 is a deuterated form of 22(R)-hydroxycholesterol.
生化/生理作用
22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand and is a key for the receptor activation.. 22(R)-HC promotes mesenchymal stem cell osteogenesis along with other oxysterols. It also regulates cholesterol homeostasis and suppresses prostate tumor progression. Low levels of 22(R)-HC is observed in Alzheimer′s disease and may be implicated in neuroinflammation and neurodegenerative diseases.
包装
5 mL Amber Glass Screw Cap Vial (700052P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
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