InChI
1S/C29H48O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,20,22-23,25-26,30H,8,10-18H2,1-7H3/t20-,22-,23+,25+,26+,28-,29-/m1/s1
InChI key
CHGIKSSZNBCNDW-QGBOJXOESA-N
SMILES string
C[C@]12CCC([C@](CC[C@H](O)C3(C)C)(C)C3CC4)=C4C1CC[C@]2([H])[C@]([H])(C)CCC=C(C)C
description
4,4-dimethyl-cholest-8(9),24-dien-3β-ol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700073P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−70°C
General description
14去甲基羊毛甾醇作为胆固醇生物合成的中间体。用于刺激卵母细胞进行减数分裂。14去甲基羊毛甾醇调节卵丘扩展。
Application
14-去甲基羊毛甾醇已被用于降低癌细胞活力和增加癌细胞对厄洛替尼的敏感性。
Packaging
5 mL琥珀色玻璃螺旋盖样品瓶(700073P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
The chemistry of the vitamins (1965)
Yen and Jaffe's Reproductive Endocrinology: Physiology, Pathophysiology, and Clinical Management (2009)
Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation
Sukhanova A, et al.
Cancer Discovery, 3(1), 96-111 (2013)
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