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关于此项目
经验公式（希尔记法）:
C27H37D7O
化学文摘社编号:
分子量:
391.68
MDL number:
UNSPSC Code:
41141804
NACRES:
NA.25
Assay:
>99% (TLC)
Form:
powder
产品名称
7-去氢胆甾醇-d7, Avanti Research™ - A Croda Brand
description
7-dehydrocholesterol-d7
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700116P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−70°C
SMILES string
O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@@H](CC[C@@H]4[C@@H](CCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])C)C3=CC=C2C1)C)C
InChI
1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1/i1D3,2D3,18D
InChI key
UCTLRSWJYQTBFZ-UDEPUTHCSA-N
General description
7-脱氢胆固醇（7-DHC）是一种胆固醇前体，位于基底表皮角质形成细胞中。7DHC在紫外光B存在下发生光解生成维生素原D3。脱氢胆固醇还原酶（DHCR7）催化7-DHC的C（7-8）双键还原为胆固醇。7-脱氢胆固醇是7-脱氢胆固醇的氘代衍生物。
Application
7-脱氢胆固醇-d7已被用于：
- 作为内标物：加标衣藻CC-125脂质提取物进行质谱分析
- 用于培养细胞氧化甾醇分析的液相色谱-质谱（LC-MS）中
- 用于气相色谱/质谱（GC/MS）分析用于处理和标记SRD-1细胞（中国仓鼠卵巢（CHO）突变细胞系）
Biochem/physiol Actions
7-脱氢胆固醇（7-DHC）用作微生物维生素D3生产的前体。 7-脱氢胆固醇还原酶（DHCR7）功能受损导致7-DHC积累，并与Smith-Lemli-Opitz综合征（SLOS）有关。
Packaging
5 mL琥珀色玻璃螺旋盖小瓶(700116P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
美国出口管控产品
此项目有
Hanul Kim et al.
Frontiers in microbiology, 6, 54-54 (2015-03-12)
Concern about global warming has prompted an intense interest in developing economical methods of producing biofuels. Microalgae provide a promising platform for biofuel production, because they accumulate high levels of lipids, and do not compete with food or feed sources.
Andrzej T Slominski et al.
PloS one, 4(2), e4309-e4309 (2009-02-05)
Since P450scc transforms 7-dehydrocholesterol (7DHC) to 7-dehydropregnenolone (7DHP) in vitro, we investigated sequential 7DHC metabolism by adrenal glands ex vivo. There was a rapid, time- and dose-dependent metabolism of 7DHC by adrenals from rats, pigs, rabbits and dogs with production
Xiao-Jing Guo et al.
Biotechnology for biofuels, 11, 192-192 (2018-07-22)
7-Dehydrocholesterol (7-DHC) has attracted increasing attentions due to its great medical value and the enlarging market demand of its ultraviolet-catalyzed product vitamin D3. Microbial production of 7-DHC from simple carbon has been recognized as an attractive complement to the traditional
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 700116P-1MG | 04061835189441 |