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经验公式(希尔记法):
C27H39D7O3
化学文摘社编号:
分子量:
425.70
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141804
Assay:
>99% (TLC)
Form:
powder
产品名称
7α,24(R/S)-dihydroxycholesterol-d7, 7α,24(R/S)-dihydroxycholesterol-d7, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700119P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700119P
shipped in
dry ice
storage temp.
−20°C
General description
7α,24(R/S)-dihydroxycholesterol-d7 is a deuterated derivative of 7α,24(R/S)-dihydroxycholesterol and is a oxysterol.
Biochem/physiol Actions
7α,24(R/S)-dihydroxycholesterol is a racemic mixture. 7α,24(S)-dihydroxycholesterol (7α,24(S)-diOHC) is synthesized from 24(S)-OHC in the presence of enzyme oxysterol 7-α-hydroxylase 2 (CYP39A1). 7α,24(S)-diOHC is a ligand for liver X receptor (LXR).
Packaging
5 mL Amber Glass Screw Cap Vial (700119P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Simple, stereocontrolled syntheses of 24 (S), 25-epoxy-22 (R)-hydroxycholesterol, 22 (R), 24 (S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs
Corey EJ and Grogan MJ
Tetrahedron Letters null
Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma
Guillemot-Legris O, et al.
Scientific Reports null
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