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经验公式(希尔记法):
C27H39D7O3
化学文摘社编号:
分子量:
425.70
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141804
Assay:
>99% (TLC)
Form:
powder
产品名称
7α,24(R/S)-dihydroxycholesterol-d7, 7α,24(R/S)-dihydroxycholesterol-d7, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700119P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700119P
shipped in
dry ice
storage temp.
−20°C
General description
7α,24(R/S)-dihydroxycholesterol-d7 is a deuterated derivative of 7α,24(R/S)-dihydroxycholesterol and is a oxysterol.
Biochem/physiol Actions
7α,24(R/S)-dihydroxycholesterol is a racemic mixture. 7α,24(S)-dihydroxycholesterol (7α,24(S)-diOHC) is synthesized from 24(S)-OHC in the presence of enzyme oxysterol 7-α-hydroxylase 2 (CYP39A1). 7α,24(S)-diOHC is a ligand for liver X receptor (LXR).
Packaging
5 mL Amber Glass Screw Cap Vial (700119P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma
Guillemot-Legris O, et al.
Scientific Reports null
Simple, stereocontrolled syntheses of 24 (S), 25-epoxy-22 (R)-hydroxycholesterol, 22 (R), 24 (S)-dihydroxycholesterol and diastereomers, new ligands for binding and activation of LXRs
Corey EJ and Grogan MJ
Tetrahedron Letters null
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