产品名称
菜油甾醇, Avanti Research™ - A Croda Brand 700126P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (700126P-1mg)
pkg of 1 × 10 mg (700126P-10mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 700126P
运输
dry ice
储存温度
−20°C
SMILES字符串
OC1CCC2(C3C(C4C(C(CC4)C(CCC(C(C)C)C)C)(CC3)C)CC=C2C1)C
InChI
1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3
InChI key
SGNBVLSWZMBQTH-UHFFFAOYSA-N
一般描述
菜油甾醇是一种植物甾醇，是胆固醇的类似物和油菜素甾醇（BR）的前体。diminute/dwarf1酶介导了从24-亚甲基胆固醇进行菜油甾醇的合成。菜油甾醇在胆固醇侧链的C-24位上具有甲基基团。
应用
菜油甾醇可作为一种植物甾醇用于检测其对乳腺癌细胞中肝脏X受体α（LXRA）转录激活的影响。它可在液相色谱多反应监测（LC-MRM）分析中作为甾醇标准品用于生成校准曲线。
生化/生理作用
菜油甾醇可降低乳糜微粒、低密度脂蛋白（LDL）和极低密度脂蛋白（VLDL）-apoB100的水平。高比例的菜油甾醇/谷甾醇可提高棉纤维的纤维伸长率。
包装
5 mL琥珀色玻璃螺旋盖小瓶（700126P-10mg）
5 mL琥珀色玻璃螺旋盖小瓶（700126P-1mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Shasha Deng et al.
Science China. Life sciences, 59(2), 183-193 (2016-01-25)
Phytosterols play an important role in plant growth and development, including cell division, cell elongation, embryogenesis, cellulose biosynthesis, and cell wall formation. Cotton fiber, which undergoes synchronous cell elongation and a large amount of cellulose synthesis, is an ideal model
Priyadarshini Chakrabarti et al.
Metabolomics : Official journal of the Metabolomic Society, 15(10), 127-127 (2019-09-21)
Significant annual honey bee colony losses have been reported in the USA and across the world over the past years. Malnutrition is one among several causative factors for such declines. Optimal nutrition serves as the first line of defense against
U Klahre et al.
The Plant cell, 10(10), 1677-1690 (1998-10-08)
We have identified the function of the Arabidopsis DIMINUTO/DWARF1 (DIM/DWF1) gene by analyzing the dim mutant, a severe dwarf with greatly reduced fertility. Both the mutant phenotype and gene expression could be rescued by the addition of exogenous brassinolide. Analysis
Laura Calpe-Berdiel et al.
Atherosclerosis, 203(1), 18-31 (2008-08-12)
Plant sterols and stanols (phytosterols/phytostanols) are known to reduce serum low-density lipoprotein (LDL)-cholesterol level, and food products containing these plant compounds are widely used as a therapeutic dietary option to reduce plasma cholesterol and atherosclerotic risk. The cholesterol-lowering action of
Samantha A Hutchinson et al.
International journal of molecular sciences, 20(13) (2019-07-05)
Low fruit and vegetable consumption and high saturated fat consumption causes elevated circulating cholesterol and are breast cancer risk factors. During cholesterol metabolism, oxysterols form that bind and activate the liver X receptors (LXRs). Oxysterols halt breast cancer cell proliferation
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