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关于此项目
经验公式（希尔记法）:
C27H40D6O3
化学文摘社编号:
分子量:
424.69
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Assay:
>99% (TLC)
Form:
powder
产品名称
7α,27-dihydroxycholesterol-d6, Avanti Research™ - A Croda Brand
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700136P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
deuterated lipids
shipped in
dry ice
storage temp.
−20°C
General description
7α,27-dihydroxycholesterol (7α,27-di-OHC) is synthesized by the hydroxylation of 27-hydroxycholesterol (27-OHC). It is an oxysterol with side chains oxidized and is a structural isomer of 7α,25-dihydroxycholesterol. 7α,27-dihydroxycholesterol-d6 is a deuterated derivative of 7α,27-di-OHC.
Application
7α,27-dihydroxycholesterol-d6 has been used as a deuterated internal standard in liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS) for human plasma oxysterol analysis.
Biochem/physiol Actions
7α,27-dihydroxycholesterol (7α,27-di-OHC) is a ligand for Epstein-Barr virus-induced gene 2 (EBI2). 7α27-di-OHC is implicated in neurological disease, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human cerebrospinal fluid (CSF) samples. The levels of 7α,27-di-OHC decreases in lipopolysaccharide activation.
Packaging
5 mL Amber Glass Screw Cap Vial (700136P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3