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经验公式（希尔记法）:
C27H40D6O3
化学文摘社编号:
分子量:
424.69
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141804
Assay:
>99% (TLC)
Form:
powder
产品名称
7β,27-dihydroxycholesterol-d6, Avanti Research™ - A Croda Brand 700137P, powder
storage temp.
−20°C
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700137P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700137P
shipped in
dry ice
General description
7β,27-dihydroxycholesterol-d6 is a deuterated derivative of 7β,27-dihydroxycholesterol. 7β,27-dihydroxycholesterol is a substrate for enzyme 11β-hydroxysteroid dehydrogenases (11β-HSDs).
Application
7β,27-dihydroxycholesterol-d6 has been used as an internal standard in ultra-performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS).
Biochem/physiol Actions
7β,27-dihydroxycholesterol (7β27OHC) serves as a ligand for retinoid-related orphan receptor γ (RORγ). 7β27OHC is also involved in smoothened (Smo) functionality.
Packaging
5 mL Amber Glass Screw Cap Vial (700137P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
此项目有
Katharina R Beck et al.
Journal of lipid research, 60(9), 1535-1546 (2019-07-06)
Oxysterols previously were considered intermediates of bile acid and steroid hormone biosynthetic pathways. However, recent research has emphasized the roles of oxysterols in essential physiologic processes and in various diseases. Despite these discoveries, the metabolic pathways leading to the different
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