710332C
Avanti
14:0 Cardiolipin (ammonium salt)
Avanti Research™ - A Croda Brand
别名:
1,1′,2,2′-tetramyristoyl cardiolipin (ammonium salt); 1,1′,2,2′-tetratetradecanoyl cardiolipin (ammonium salt); CL(1′-[14:0/14:0],3′-[14:0/14:0])
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About This Item
经验公式（希尔记法）:
C65H132N2O17P2
CAS Number:
分子量:
1275.69
MDL编号:
UNSPSC代码:
51191904
NACRES:
NA.25
Product Name
14:0 Cardiolipin (ammonium salt), 1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt), chloroform
方案
>99% (TLC)
表单
solution
包装
pkg of 1 × 2.5 mL (710332C-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 710332C
浓度
10 mg/mL (710332C-25mg)
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
一般描述
14:0 Cardiolipin is an acidic phospholipid. Structurally, cardiolipin comprises three glycerol moieties and four acyl chains and is localized in the inner membrane of mitochondria. 14:0 Cardiolipin contains four myristic acid as acyl chain.
应用
14:0 Cardiolipin (1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt)) has been used:
- as a standard in tandem mass spectrometry
- in the preparation of membrane proximal region (MPR) of human immunodeficiency virus (HIV-1) glycoprotein 41 (gp41)-lipopeptide conjugate and liposomes
- as a component of micelle for suspending C8 ceramide substrate in ceramide kinase assay
生化/生理作用
Cardiolipin (CL) plays a key role in oxidative phosphorylation. CL is essential for energy production and in the activation of apoptosis. Deficiency of CL is associated with the development of diabetes and age-related heart failure. Anomalies associated with CL composition is observed in Barth Syndrome (BTHS).
包装
5 mL Clear Glass Sealed Ampule (710332C-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system, Liver,Kidney
WGK
WGK 3
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