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关于此项目
经验公式（希尔记法）:
C65H124Na2O17P2
化学文摘社编号:
分子量:
1285.60
MDL number:
NACRES:
NA.25
UNSPSC Code:
51191904
产品名称
14:0 Cardiolipin (sodium salt), 1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium salt), chloroform
assay
>99% (TLC)
form
solution
packaging
pkg of 1 × 2.5 mL (750332C-25mg)
pkg of 2 × 4 mL (750332C-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 750332C
concentration
10 mg/mL (750332C-25mg)
25 mg/mL (750332C-200mg)
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
Application
14:0 Cardiolipin (sodium salt) has been used for the mass spectrometry (MS) analysis to determine the structure of lipid A.
General description
Cardiolipin, the mitochondrial-specific phospholipid, helps maintain mitochondrial function, membrane potential and structural support for the inner mitochondrial membrane and the proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy (Barth syndrome). Cardiolipin has also been shown as a signaling molecule in apoptosis.
Packaging
5 mL Clear Glass Sealed Ampule (750332C-200mg)
5 mL Clear Glass Sealed Ampule (750332C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Rapid lipid a structure determination via surface acoustic wave nebulization and hierarchical tandem mass spectrometry algorithm
Yoon SH, et al.
Rapid Communications in Mass Spectrometry, 30(23), 2555-2560 (2016)
Vladimir B Ritov et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 831(1-2), 63-71 (2005-12-13)
Cardiolipin is a phospholipid that is specific to the inner mitochondrial membrane and essential for numerous mitochondrial functions. Accordingly, a quantitative assay for cardiolipin can be a valuable aspect of assessing mitochondrial content and functional capacity. The current study was
Role of cardiolipin alterations in mitochondrial dysfunction and disease
Chicco AJ and Sparagna GC
American Journal of Physiology. Cell Physiology, 292(1), C33-C44 (2007)
Na Li et al.
Analytical chemistry, 91(24), 15873-15882 (2019-11-14)
The matrix plays a prominent role in expanding the ability of matrix assisted laser desorption/ionization mass spectrometry (MALDI MS). However, on account of the unclarity of necessary properties of the matrix in MALDI MS, development of a new matrix is
Yuchen Sun et al.
Metabolites, 9(11) (2019-11-07)
Extracellular vesicles (EVs) consist of lipid bilayers, occur in various biofluids, and are invaluable in biomarker screening. Liquid chromatography coupled with high-resolution mass spectrometry (LC-MS) was recently used to study comprehensive EV lipid profiles in vitro. The aim of this
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