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关于此项目
经验公式（希尔记法）:
C49H86N2O11PNa
化学文摘社编号:
分子量:
933.18
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
16:0 PE MCC, 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt), chloroform
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 2.5 mL (780200C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 780200C
concentration
10 mg/mL (780200C-25mg)
application(s)
advanced drug delivery
shipped in
dry ice
storage temp.
−20°C
Application
16:0 PE MCC（1，2-二棕榈酰-sn-甘油-3-磷酸乙醇胺-N-4-（对马来酰亚胺基甲基）环己烷-羧酰胺）可用于：
- 制备与人免疫缺陷病毒（HIV-1）包膜糖蛋白三聚体结合的脂质体
- 制备寡核苷酸修饰囊泡
- 扁平硅片的功能化
- 脂质囊泡制备
Biochem/physiol Actions
功能化脂质体中的1，2-二棕榈酰基-sn-甘油-3-磷酸乙醇胺-N-[4-（对马来酰亚胺基甲基）环己烷-羧酰胺]（1，2-双（二苯基膦基）乙烷(DPPE)-MCC）有助于共价连接通过马来酰亚胺基团。它在肽转运研究中充当载体。
General description
1，2-二棕榈酰基-sn-甘油-3-磷酸乙醇胺-N-[4-（对马来酰亚胺基甲基）环己烷-羧酰胺]（16:0 PE MCC）是一种脂质，其脂质包含通过其磷酸基团与两个棕榈酸连接的磷酸乙醇胺并通过其氨基形成马来酰亚胺部分。马来酰亚胺基团是硫醇受体，而16:0 PE MCC是基于马来酰亚胺的脂化试剂。
Packaging
5 mL透明玻璃密封安瓿（780200C-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
wgk
WGK 3
法规信息
新产品
此项目有
J T Elliott et al.
Bioconjugate chemistry, 11(6), 832-841 (2000-11-23)
Two maleimide-containing diacylglycerol derivatives were synthesized to permit the anchoring of short peptides and longer polypeptides to phospholipid bilayers and membranes. The maleimide was introduced at the site normally occupied by a phospholipid headgroup. The first lipid, the dipalmitoyl ester
Malin Edvardsson et al.
Analytical chemistry, 81(1), 349-361 (2008-11-28)
A novel setup was recently developed, combining quartz crystal microbalance with dissipation monitoring (QCM-D) and optical reflectometry for measurements on one and the same surface of, for example, biomolecular adlayers and interactions ( Rev. Sci. Instr. 2008 , 79 075107
Bärbel Lorenz et al.
Biophysical chemistry, 150(1-3), 54-63 (2010-03-12)
A versatile model system to study membrane-membrane interactions in great detail is introduced. Based on colloidal probe microscopy with membrane covered spherical probes attached to tip-less cantilevers the interaction forces and adhesion energies are quantified down to single molecule resolution.
Xiaoming Zhang et al.
Biochemical and biophysical research communications, 349(3), 920-924 (2006-09-15)
Human serum albumin (HSA) patterns have been successfully fabricated for the deposition of lipid bilayer, 1,2-dimyristoyl-sglycerophosphate (DMPA), by making use of the micro-contact printing (microCP) technique and liposome fusion. Confocal laser scanning microscopy (CLSM) results indicate that lipid bilayer has
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 172(3), 872-878 (2013-10-22)
The aim of the present study was the in vivo evaluation of thiomer-coated liposomes for an oral application of peptides. For this purpose, salmon calcitonin was chosen as a model drug and encapsulated within liposomes. Subsequently, the drug loaded liposomes
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