产品名称
Upstate脂混合物, Synthetic Phospholipid Blend for PTEN, PDK1, and Akt1/PKBα Assay Kits, contains DOPC/DOPS (1:1, wt%), powder
form
powder
packaging
pkg of 1 × 5 mg (790595P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 790595P
lipid type
formulation
phospholipids
shipped in
dry ice
storage temp.
−20°C
General description
Upstate脂混合物包含比例为1:1wt%的DOPC:DOPS。1,2-二油酰-sn-甘油-3-磷胆碱(DOPC)和1,2-二油酰-sn-甘油-3-[磷-l-丝氨酸](DOPS)是真核细胞膜的重要成分。
Application
在磷脂酰肌醇4-激酶β(PI4Kβ)和磷脂酰肌醇3-激酶β(PI3Kβ)活性研究中，已使用Upstate脂混合物生成L-α-磷脂酰肌醇(PI):DOPS:DOPC。
Biochem/physiol Actions
1,2-二油酰-sn-甘油-3-磷胆碱(DOPC)和1,2-二油酰-sn-甘油-3-[磷-l-丝氨酸](DOPS)双层是稳定的，可用于生成多层囊泡。
Packaging
5 mL棕色玻璃螺旋盖小瓶（790595P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Molecular volumes of DOPC and DOPS in mixed bilayers of multilamellar vesicles
Murugova TN and Balgavy P
Physical Chemistry Chemical Physics, 16(34), 18211-18216 (2014)
Multistep compositional remodeling of supported lipid membranes by interfacially active phosphatidylinositol kinases
Tabaei SR, et al.
Analytical Chemistry, 88(10), 5042-5045 (2016)
Characterization of the interface of binary mixed DOPC: DOPS liposomes in water: The impact of charge condensation
Lutgebaucks C, et al.
J. Chem. Phys. , 146(4), 044701-044701 (2017)
Design and structural characterization of potent and selective inhibitors of phosphatidylinositol 4 kinase IIIbeta
Rutaganira FU, et al.
Journal of Medicinal Chemistry, 59(5), 1830-1839 (2016)
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