Product Name
2-OHOA, 2-hydroxyoleic acid (sodium salt), powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 g (791056P-1g)
制造商/商品名称
Avanti Research™ - A Croda Brand 791056P
脂质类型
neutral lipids
neutral glycerides
运输
dry ice
储存温度
−20°C
一般描述
2-hydroxyoleic acid (2-OHOA) is a synthetic and non-β oxidation-metabolizable oleic acid derivative. It contains 18 carbon atoms in its fatty acid chain length.
应用
2-hydroxyoleic acid (2-OHOA) is suitable for use:
- to study its antihypertensive action in adult spontaneously hypertensive rats (SHRs)
- to study the chemical structure-effect relation of 2-OHOA in the reduction of body weight in rats
- as an antitumor compound, to study its effect on xenografts lipidome based on imaging mass spectrometry (IMS)
生化/生理作用
2-Hydroxy Oleic Acid is an inducer of cell cycle arrest and apoptosis in several cancer cell lines, including glioma, leukemia, breast and colon cancer lines. 2-Hydroxy Oleic Acid increases sphingomyelin (SM) levels in the membranes of tumor cells, which typically display decreased SM membrane content, and remodeled membranes, compared with normal cells. The compound has no effect on SM levels in non-cancer cells.
2-hydroxyoleic acid (2-OHOA) acts as a potential antihypertensive agent. Oral administration of 2-OHOA is used to reduce body weight.
包装
20 mL Clear Glass Screw Cap Vial (791056P-1g)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持