791268P
Avanti
DTPA-BSA (Gd)
Avanti Research™ - A Croda Brand
别名:
（二亚乙基三胺五乙酸）-双（硬脂酰胺）（gd盐）; Gd-DTPA-BSA
产品名称
DTPA-BSA (Gd), DTPA-bis(stearylamide) (gadolinium salt), powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 100 mg (791268P-100mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 791268P
运输
dry ice
储存温度
−20°C
一般描述
DTPA-BSA(Gd)（二乙烯三胺五乙酸-双(硬脂酰胺)(钆盐)）是一种具有顺磁性的两亲分子。
应用
DTPA-BSA(Gd)（二乙烯三胺五乙酸-双(硬脂酰胺)(钆盐)）已用于：
- 制备非靶向(NT)钆修饰两亲性多肽胶束(PAM)，用于动脉粥样硬化病变的磁共振成像(MRI)
- 在小干扰RNA(siRNA)包埋类脂纳米粒(LLN)制备中用作MRI造影剂
- 在顺磁性鞘脂激活蛋白C(saposin C)和二油酰磷脂酰丝氨酸(SapC-DOPS)囊泡的制备中作为MRI造影剂用于多形性胶质母细胞瘤(GBM)成像
生化/生理作用
Gd-DTPA-BSA可用作磁共振成像(MRI)造影剂，钆离子可缩短纵向弛豫时间使影像更为明亮。
包装
5 mL 棕色玻璃螺旋盖样品瓶 (791268P-100mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents
Luo X, et al.
Nanoscale, 9(4), 1575-1579 (2017)
Sang Pil Yoo et al.
ACS omega, 1(5), 996-1003 (2016-12-06)
The leading causes of morbidity and mortality globally are cardiovascular diseases, and nanomedicine can provide many improvements including disease-specific targeting, early detection, and local delivery of diagnostic agents. To this end, we designed fibrin-binding, peptide amphiphile micelles (PAMs), achieved by
Gadolinium-functionalized peptide amphiphile micelles for multimodal imaging of atherosclerotic lesions
Yoo SP, et al.
ACS Omega, 1(5), 996-1003 (2016)
Imaging of brain tumors with paramagnetic vesicles targeted to phosphatidylserine
Winter PM, et al.
Journal of Magnetic Resonance Imaging : JMRI, 41(4), 1079-1087 (2015)
Patrick M Winter et al.
Journal of magnetic resonance imaging : JMRI, 41(4), 1079-1087 (2014-05-07)
To investigate paramagnetic saposin C and dioleylphosphatidylserine (SapC-DOPS) vesicles as a targeted contrast agent for imaging phosphatidylserine (PS) expressed by glioblastoma multiforme (GBM) tumors. Gd-DTPA-BSA/SapC-DOPS vesicles were formulated, and the vesicle diameter and relaxivity were measured. Targeting of Gd-DTPA-BSA/SapC-DOPS vesicles
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