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Merck
CN

791268P

Avanti

DTPA-BSA (Gd)

Avanti Research - A Croda Brand

别名:

(二亚乙基三胺五乙酸)-双(硬脂酰胺)(gd盐); Gd-DTPA-BSA

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关于此项目

经验公式(希尔记法):
C50H94GdN5O8
化学文摘社编号:
分子量:
1050.56
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

DTPA-BSA (Gd), DTPA-bis(stearylamide) (gadolinium salt), powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 mg (791268P-100mg)

manufacturer/tradename

Avanti Research - A Croda Brand 791268P

shipped in

dry ice

storage temp.

−20°C

Application

DTPA-BSA(Gd)(二乙烯三胺五乙酸-双(硬脂酰胺)(钆盐))已用于:
  • 制备非靶向(NT)钆修饰两亲性多肽胶束(PAM),用于动脉粥样硬化病变的磁共振成像(MRI)
  • 在小干扰RNA(siRNA)包埋类脂纳米粒(LLN)制备中用作MRI造影剂
  • 在顺磁性鞘脂激活蛋白C(saposin C)和二油酰磷脂酰丝氨酸(SapC-DOPS)囊泡的制备中作为MRI造影剂用于多形性胶质母细胞瘤(GBM)成像

Biochem/physiol Actions

Gd-DTPA-BSA可用作磁共振成像(MRI)造影剂,钆离子可缩短纵向弛豫时间使影像更为明亮。

General description

DTPA-BSA(Gd)(二乙烯三胺五乙酸-双(硬脂酰胺)(钆盐))是一种具有顺磁性的两亲分子。

Packaging

5 mL 棕色玻璃螺旋盖样品瓶 (791268P-100mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

存储类别

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

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X Luo et al.
Nanoscale, 9(4), 1575-1579 (2017-01-10)
Multi-functional nanomaterials possess unique properties, facilitating both therapeutic and diagnostic applications among others. Herein, we developed dual-functional lipid-like nanoparticles for simultaneous delivery of mRNA and magnetic resonance imaging (MRI) contrast agents in order to express functional proteins and provide real-time
Gadolinium-functionalized peptide amphiphile micelles for multimodal imaging of atherosclerotic lesions
Yoo SP, et al.
ACS Omega, 1(5), 996-1003 (2016)
Imaging of brain tumors with paramagnetic vesicles targeted to phosphatidylserine
Winter PM, et al.
Journal of Magnetic Resonance Imaging : JMRI, 41(4), 1079-1087 (2015)
Geralda A F van Tilborg et al.
Bioconjugate chemistry, 17(3), 741-749 (2006-05-18)
Apoptosis, or programmed cell death, plays an important role in the etiology of a variety of diseases, including cancer and myocardial infarction. Visualization of apoptosis would allow both early detection of therapy efficiency and evaluation of disease progression. To that
Sang Pil Yoo et al.
ACS omega, 1(5), 996-1003 (2016-12-06)
The leading causes of morbidity and mortality globally are cardiovascular diseases, and nanomedicine can provide many improvements including disease-specific targeting, early detection, and local delivery of diagnostic agents. To this end, we designed fibrin-binding, peptide amphiphile micelles (PAMs), achieved by

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