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关于此项目
经验公式（希尔记法）:
C39H67D7NaO10 P
化学文摘社编号:
分子量:
764.01
MDL number:
NACRES:
NA.25
UNSPSC Code:
41141825
产品名称
15:0-18:1-d7-PG, Avanti Research™ - A Croda Brand 791640C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (791640C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 791640C
concentration
1 mg/mL (791640C-1mg)
shipped in
dry ice
storage temp.
−20°C
Application
15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] (sodium salt),) has been used:
- as a component of extraction solvent for lipid isolation from biological samples
- as an internal standard to spike cell lysate and to quantify lipid species using fourier transform mass spectrometry (FTMS) analysis
- as an isotopically labeled lipid internal standard for correction of lipids detected in lipid droplets using shotgun mass spectrometry analysis
Biochem/physiol Actions
Phosphatidylglycerol (PG) plays a key role in photosynthesis. Cardiolipin is synthesized from PG. PG mediates many mitochondrial functions.
General description
15:0-18:1-d7-PG (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-[phospho-rac-(1′-glycerol)] is a deuterated phospholipid. The lipid comprises phosphatidylglycerol attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylglycerol is anionic phospholipid and is associated with thylakoids, microsomal and mitochondrial membrane.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.
Packaging
2 mL Amber Glass Sealed Ampule (791640C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品（2类）
危险化学品
此项目有
Shin-Ya Morita et al.
Scientific reports, 5, 11737-11737 (2015-07-01)
Phosphatidylglycerol (PG) and cardiolipin (CL) are synthesized in mitochondria and regulate numerous biological functions. In this study, a novel fluorometric method was developed for measuring PG and CL using combinations of specific enzymes and Amplex Red. This assay quantified the
Florian Geltinger et al.
GeroScience, 42(1), 19-38 (2019-11-05)
Originally Lipid droplets (LDs) were considered as being droplets for lipid storage only. Increasing evidence, however, demonstrates that LDs fulfill a pleiotropy of additional functions. Among them is the modulation of protein as well as lipid homeostasis. Under unfavorable pro-oxidative
Ya Xie et al.
Food chemistry, 319, 126547-126547 (2020-03-18)
In this research, a novel ultrasound-assisted extraction (USAE) method using a one-phase solvent (isopropanol, IPA) combined with liquid chromatography-electrospray ionization quadrupole time-of-flight mass spectrometry (LC-ESI-QToF-MS) was developed for exhaustive profiling of egg yolk lipids, which are considered to be essential
Tong Liu et al.
Expert review of proteomics, 17(3), 233-242 (2020-04-21)
Background: Colorectal cancer (CRC) represents a third leading cause of cancer-related death worldwide. The reliable diagnostic biomarkers for detecting CRC at early stage is critical for decreasing the mortality.Method: A conjunctive lipidomic approach was employed to investigate the differences in
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using
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