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关于此项目
经验公式（希尔记法）:
C27H52O5
化学文摘社编号:
分子量:
456.70
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
12:0 DG, Avanti Research™ - A Croda Brand
SMILES string
O([C@H](COC(=O)CCCCCCCCCCC)CO)C(=O)CCCCCCCCCCC
InChI
1S/C27H52O5/c1-3-5-7-9-11-13-15-17-19-21-26(29)31-24-25(23-28)32-27(30)22-20-18-16-14-12-10-8-6-4-2/h25,28H,3-24H2,1-2H3/t25-/m0/s1
InChI key
OQQOAWVKVDAJOI-VWLOTQADSA-N
description
1,2-dilauroyl-sn-glycerol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (800812P-10mg)
pkg of 1 × 200 mg (800812P-200mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
neutral glycerides
neutral lipids
shipped in
dry ice
storage temp.
−20°C
Application
12:0 DG has been used as an internal standard for spiking serum samples for liquid chromatography–mass spectrometry analysis. It may be used as an internal standard for spiking RAW 264.7 cells for mass spectroscopy studies and in reverse phase liquid chromatography coupled mass spectrometer for lipidomics studies of human plasma and serum samples.
Biochem/physiol Actions
1,2-dilauroyl-sn-glycerol is a polymerization initiator used in the synthesis of (R)-3-((2-bromo-2-methylpropanoyl)oxy)propane-1,2-diyl didodecanoate (BMPD). sn-1,2-diacylglycerols are prime regulators of biological functions especially in platelets. They also activate protein kinase C.
General description
sn-1,2-diacylglycerols comprise short saturated acyl side chains (C4-C10) and 12:0 DG is also called 1,2-dilauroyl-sn-glycerol.
Packaging
5 mL Amber Glass Screw Cap Vial (800812P-10mg)
5 mL Amber Glass Screw Cap Vial (800812P-200mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm
Callender HL, et al.
Analytical Chemistry, 79(1), 263-272 (2007)
Lipid Profile Characterization and Lipoprotein Comparison of Extracellular Vesicles from Human Plasma and Serum
Sun Y, et al.
Metabolites, 9(11), 259-259 (2019)
Lipidated polymers for the stabilization of cubosomes: nanostructured drug delivery vehicles
Grace JL, et al.
Chemical Communications (Cambridge, England), 53(76), 10552-10555 (2017)
Structural Properties of 1, 2-Diacyl-sn-glycerol in Bulk and at the Water Interface by Molecular Dynamics
van Buuren AR, et al.
Langmuir, 11(8), 2957-2965 (1995)
Serum lipidome analysis of healthy beagle dogs receiving different diets
Boretti FS, et al.
Metabolomics, 16(1), 1-1 (2020)
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