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关于此项目
经验公式(希尔记法):
C26H34 N4O5
化学文摘社编号:
分子量:
482.57
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
NBD AA, Avanti Research™ - A Croda Brand
lipid type
fluorescent lipids
bioactive lipids
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810106C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
1 mg/mL (810106C-1mg)
shipped in
dry ice
storage temp.
−70°C
General description
The endocannabinoid pathway influences behavior, lipogenesis, embryologic development, and pathophysiological effects including pain, inflammation, stress, obesity, and non-alcoholic fatty liver disease. Endogenous endocannabinoids including arachidonoylethanolamide (anandamide, AEA) and 2-arachidonoylglycerol (2-AG) are derived from arachidonic acid (AA). Fluorescent NBD-AA and NBD-AEA analogues are direct probes that can be used for visualizing the uptake, intracellular trafficking, and targeting of these molecules by living cells, as well as measuring the binding of endocannabinoids to cytosolic binding proteins. Importantly, direct binding studies show the affinities of the fluorescent analogues are in the same range as the respective unlabeled ligands. Fluorescent endocannabinoid probes are useful for mapping the impact of various treatments, inhibitors, etc on endocannabinoid uptake and distribution in living cells.
Packaging
5 mL Amber Glass Screw Cap Vial/Argon/Foil Bag 810106C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
法规信息
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