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关于此项目
经验公式(希尔记法):
C45H80N5O11P
化学文摘社编号:
分子量:
898.12
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
Egg NBD PE, Avanti Research™ - A Croda Brand 810118C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810118C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810118C
concentration
1 mg/mL (810118C-1mg)
shipped in
dry ice
storage temp.
−20°C
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General description
The phosphatidylethanolamine (PE) is a zwitterionic phospholipid. Its headgroup is provided with a phosphate, that is negatively charged and a free amine, that is positively charged. PE is one of the widely distributed glycerophospholipid in eukaryotic cells.
Application
Egg NBD PE is suitable to use as an additive in dimethylformamide (DMF) to compare the effects of nystatin on the diffusion of NBD-Nys and NBD-PE. It has also been used to monitor lipid extraction from liposomes for lipid transfer assay.
Biochem/physiol Actions
Phosphatidylethanolamine (PE) helps to activate factor (F)X and PT, thereby stimulating thrombosis. It serves as an anticoagulant. PE is essential for the surface expression of γ-aminobutyric acid type A receptors (GABAARs) in cultured neurons.
Packaging
5 mL Amber Glass Screw Cap Vial (810118C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
易制毒化学品(2类)
危险化学品
此项目有
Proteostasis maintenance of Cys-loop receptors
Advances in Protein Chemistry and Structural Biology, 103(3), 1- 23 (2016)
Antibodies and Diagnostic Tests in Antiphospholipid Syndrome
Systemic Lupus Erythematosus, 495- 501 (2016)
Structure-function insights into direct lipid transfer between membranes by Mmm1-Mdm12 of ERMES
Kawano S, et al.
The Journal of Cell Biology, 217(3), 959-974 (2018)
Evidence for nystatin micelles in L-cell membranes from fluorescence photobleaching measurements of diffusion
O'Neill LJ, et al.
Biochemistry, 25(1), 177- 181 (1986)
Lipid-Protein Interactions in Membranes
Yeagle PL
The Membranes of Cells, 291- 334 (2016)
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