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关于此项目
经验公式（希尔记法）:
C38H64N5O11P
化学文摘社编号:
分子量:
797.92
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
18:1-06:0 NBD PC, Avanti Research™ - A Croda Brand 810132C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810132C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810132C
concentration
1 mg/mL (810132C-1mg)
shipped in
dry ice
storage temp.
−20°C
Application
18:1-06:0 NBD PC is suitable for use:
- as a component in preparing lipid solution for bilayer formation
- to use as a single donor in fluorescence resonance energy transfer (FRET) based assay
- to prepare phospholipid-coated beads
Biochem/physiol Actions
NBD‐PC can be used to probe the existence of (Rho‐labeled) protease‐activated receptor (PAR) pepducins in the outer and inner leaflets.
General description
Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine (PC) metabolism. 18:1-06:0 NBD PC is a fluorescent lipid analog/probe.
Packaging
5 mL Amber Glass Screw Cap Vial (810132C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
wgk
WGK 3
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Anticoagulant and antithrombotic properties of intracellular protease-activated receptor antagonists
Wielders SJH, et al.
Journal of Thrombosis and Haemostasis, 5(3), 571-576 (2007)
Coordinated balance of Rac1 and RhoA plays key roles in determining phagocytic appetite
Kim SY, et al.
PLoS ONE, 12(4), e0174603-e0174603 (2017)
Yuta Ryoden et al.
Journal of immunology (Baltimore, Md. : 1950), 204(3), 559-568 (2019-12-22)
In response to extracellular ATP, the purinergic receptor P2X7 mediates various biological processes, including phosphatidylserine (PtdSer) exposure, phospholipid scrambling, dye uptake, ion transport, and IL-1β production. A genome-wide CRISPR screen for molecules responsible for ATP-induced PtdSer exposure identified a transmembrane
Large scale biomimetic membrane arrays
Hansen JS, et al.
Analytical and Bioanalytical Chemistry, 395(3), 719-727 (2009)
Chung Park et al.
eLife, 8 (2019-12-04)
During human immunodeficiency virus-1 (HIV-1) infection lymphoid organ follicular dendritic cells (FDCs) serve as a reservoir for infectious virus and an obstacle to curative therapies. Here, we identify a subset of lymphoid organ sinus lining macrophage (SMs) that provide a
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