810152P
Avanti
14:0-12:0 NBD PE
Avanti Research™ - A Croda Brand
别名:
1-myristoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoethanolamine
Product Name
14:0-12:0 NBD PE, Avanti Research™ - A Croda Brand 810152P, powder
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 mg (810152P-1mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 810152P
运输
dry ice
储存温度
−20°C
一般描述
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescently labeled lipid localized to the membrane interface. The molecule contains NBD as a fluorophore moiety linked to the headgroup of phosphatidylethanolamine. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid. It is mostly enriched in brain.
生化/生理作用
Phosphoethanolamine present in cardiac myocytes plays a vital role in the prevention of cell damage after ischemia. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) supports the sensing of the Red edge excitation shift (REES) phenomenon with the unique motional and dielectric properties it possesses.
包装
5 mL Amber Glass Screw Cap Vial (810152P-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in
S C Lopes et al.
Biochimica et biophysica acta. Biomembranes, 1861(6), 1152-1161 (2019-03-07)
Mitochondrial membranes are pointed out as the site of cardiotoxic action of local anaesthetics. Its three main phospholipids components are phosphatidylcholine, phosphatidylethanolamine and cardiolipin. Cardiolipins, in eukaryotes, are only found in mitochondria and are essential for the maintenance of its
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