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关于此项目
经验公式（希尔记法）:
C37H64N5O11P
化学文摘社编号:
分子量:
785.90
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
14:0-12:0 NBD PE, Avanti Research™ - A Croda Brand 810152P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810152P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810152P
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
Phosphoethanolamine present in cardiac myocytes plays a vital role in the prevention of cell damage after ischemia. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) supports the sensing of the Red edge excitation shift (REES) phenomenon with the unique motional and dielectric properties it possesses.
General description
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescently labeled lipid localized to the membrane interface. The molecule contains NBD as a fluorophore moiety linked to the headgroup of phosphatidylethanolamine. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid. It is mostly enriched in brain.
Packaging
5 mL Amber Glass Screw Cap Vial (810152P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
S C Lopes et al.
Biochimica et biophysica acta. Biomembranes, 1861(6), 1152-1161 (2019-03-07)
Mitochondrial membranes are pointed out as the site of cardiotoxic action of local anaesthetics. Its three main phospholipids components are phosphatidylcholine, phosphatidylethanolamine and cardiolipin. Cardiolipins, in eukaryotes, are only found in mitochondria and are essential for the maintenance of its
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in
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