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关于此项目
经验公式（希尔记法）:
C39H68N5O11P
化学文摘社编号:
分子量:
813.96
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
16:0-12:0 NBD PE, Avanti Research™ - A Croda Brand 810154P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810154P-1mg)
pkg of 5 × 1 mg (810154P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810154P
shipped in
dry ice
storage temp.
−20°C
Application
16:0-12:0 NBD PE has been used in lipid extraction assay and in vitro phospholipid fluorescence resonance energy transfer (FRET) assays. It is suitable for the determination of enzyme substrate specificity of lipoteichoic acid synthase (LtaS).
Biochem/physiol Actions
Phosphoethanolamine (PE) plays a vital role in the prevention of tumor proliferation. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) monitors the Red edge excitation shift (REES) phenomenon with the unique motional and dielectric properties it possesses.
General description
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe localized at the membrane interface. It possess fluorescent NBD label attached to the headgroup of phosphatidylethanolamine (PE). PE is the parent compound for phosphatidylcholine and phosphatidylethanolamine synthesis and is mostly enriched in brain.
Packaging
5 mL Amber Glass Screw Cap Vial (810154P-1mg)
5 mL Amber Glass Screw Cap Vial (810154P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
Theoretical Study of Phosphoethanolamine: A Synthetic Anticancer Agent with Broad Antitumor Activity
Lorenzo VP, et al.
Journal of Chemistry, 2016 (2016)
María Isabel Hernández-Alvarez et al.
Cell, 177(4), 881-895 (2019-05-06)
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies from patients with non-alcoholic steatohepatitis (NASH). Moreover, reduced Mfn2
Ouma Onguka et al.
The Journal of biological chemistry, 290(20), 12744-12752 (2015-04-02)
Phosphatidylethanolamine (PE) is a major cellular phospholipid that can be made by four separate pathways, one of which resides in the mitochondrion. The mitochondrial enzyme that generates PE is phosphatidylserine decarboxylase 1 (Psd1p). The pool of PE produced by Psd1p
S C Lopes et al.
Biochimica et biophysica acta. Biomembranes, 1861(6), 1152-1161 (2019-03-07)
Mitochondrial membranes are pointed out as the site of cardiotoxic action of local anaesthetics. Its three main phospholipids components are phosphatidylcholine, phosphatidylethanolamine and cardiolipin. Cardiolipins, in eukaryotes, are only found in mitochondria and are essential for the maintenance of its
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