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关于此项目
经验公式(希尔记法):
C35H58N5O11P
化学文摘社编号:
分子量:
755.84
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
18:1-06:0 NBD PE, Avanti Research™ - A Croda Brand 810155C
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810155C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810155C
concentration
1 mg/mL (810155C-1mg)
shipped in
dry ice
storage temp.
−20°C
Application
18:1-06:0 NBD PE has been used as a liposomal supplement for protein reconstitution into liposomes and scrambling experiments. It may also be used to analyse the temporal fluorescent pattern of Chol-E-NBD.
Biochem/physiol Actions
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a vital role as a fluorescent probe in the studies of organization and dynamics of membranes. Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane.
General description
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe where the fluorescent NBD label is attached to the headgroup of phosphatidylethanolamine. The NBD moiety is known to localize to the membrane interface. Phosphoethanolamine is the second most abundant andmetabolically related aminophospholipid. It is mostly enriched in brain.
Packaging
5 mL Amber Glass Screw Cap Vial (810155C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
法规信息
易制毒化学品(2类)
危险化学品
此项目有
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
FEBS Journal, 37-50 (2012)
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et biophysica acta. General subjects, 37-50 (2012)
Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F
Alvadia C, et al.
eLife, 37-50 (2012)
Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Ferreira AK, et al.
Biomedicine and Pharmacotherapy, 37-50 (2012)
Bieong-Kil Kim et al.
Bioorganic & medicinal chemistry letters, 25(18), 3893-3896 (2015-08-06)
Cholesterol-based fluorescent lipids with ether linker were synthesized using NBD (Chol-E-NBD) or Rhodamine B (Chol-E-Rh), and the usefulnesses as fluorescent probes for tracing cholesterol-based liposomes were validated. The fluorescent intensities of liposomes containing these modified lipids were measured and observed
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