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Merck
CN

810155C

Avanti

18:1-06:0 NBD PE

Avanti Research - A Croda Brand

别名:

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoethanolamine

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关于此项目

经验公式(希尔记法):
C35H58N5O11P
化学文摘社编号:
分子量:
755.84
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

18:1-06:0 NBD PE, Avanti Research - A Croda Brand 810155C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810155C-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810155C

concentration

1 mg/mL (810155C-1mg)

shipped in

dry ice

storage temp.

−20°C

Application

18:1-06:0 NBD PE has been used as a liposomal supplement for protein reconstitution into liposomes and scrambling experiments. It may also be used to analyse the temporal fluorescent pattern of Chol-E-NBD.

Biochem/physiol Actions

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a vital role as a fluorescent probe in the studies of organization and dynamics of membranes. Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane.

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe where the fluorescent NBD label is attached to the headgroup of phosphatidylethanolamine. The NBD moiety is known to localize to the membrane interface. Phosphoethanolamine is the second most abundant andmetabolically related aminophospholipid. It is mostly enriched in brain.

Packaging

5 mL Amber Glass Screw Cap Vial (810155C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

法规信息

易制毒化学品(2类)
危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
FEBS Journal, 37-50 (2012)
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et biophysica acta. General subjects, 37-50 (2012)
Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F
Alvadia C, et al.
eLife, 37-50 (2012)
Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Ferreira AK, et al.
Biomedicine and Pharmacotherapy, 37-50 (2012)
Bieong-Kil Kim et al.
Bioorganic & medicinal chemistry letters, 25(18), 3893-3896 (2015-08-06)
Cholesterol-based fluorescent lipids with ether linker were synthesized using NBD (Chol-E-NBD) or Rhodamine B (Chol-E-Rh), and the usefulnesses as fluorescent probes for tracing cholesterol-based liposomes were validated. The fluorescent intensities of liposomes containing these modified lipids were measured and observed

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