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Merck
CN

810155P

Avanti

18:1-06:0 NBD PE

Avanti Research - A Croda Brand

别名:

1-oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoethanolamine

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关于此项目

经验公式(希尔记法):
C35H58N5O11P
化学文摘社编号:
分子量:
755.84
MDL编号:
UNSPSC代码:
12352211
NACRES:
NA.25
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方案

>99% (TLC)

表单

powder

包装

pkg of 1 × 1 mg (810155P-1mg)

制造商/商品名称

Avanti Research - A Croda Brand

运输

dry ice

储存温度

−20°C

一般描述

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescently labelled lipid with NBD attached to phosphatidylethanolamine. It is localized at the membrane interface. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid and is mostly enriched in brain.

应用

18:1-06:0 NBD PE may be used to analyse the temporal fluorescent pattern of cholesterol-E- Nitrobenzoxadiazole (Chol-E-NBD).

生化/生理作用

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is used as a fluorescent analog in the studies of organization and dynamics of membranes. Phosphoethanolamine (PE) functions as a substrate for a number of phospholipids of the cell membrane.

包装

5 mL Amber Glass Screw Cap Vial (810155P-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Ferreira AK, et al.
Biomedicine & Preventive Nutrition, 67(6), 481-487 (2013)
Fluorescent methods to study biological membranes, 37-50 (2012)
Synthesis and validation of novel cholesterol-based fluorescent lipids designed to observe the cellular trafficking of cationic liposomes
Kim BK, et al.
Bioorganic & Medicinal Chemistry, 25(18), 3893-3896 (2015)
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochim. Biophys. Acta Gen. Subj., 1831(3), 543-554 (2013)
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochim. Biophys. Acta Gen. Subj., 1861(6), 1152-1161 (2019)

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