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Merck
CN

810156C

Avanti

18:1-12:0 NBD PE

Avanti Research - A Croda Brand

别名:

1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoethanolamine

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关于此项目

经验公式(希尔记法):
C41H70N5O11P
化学文摘社编号:
分子量:
840.00
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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产品名称

18:1-12:0 NBD PE, Avanti Research - A Croda Brand 810156C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810156C-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810156C

concentration

1 mg/mL (810156C-1mg)

shipped in

dry ice

storage temp.

−20°C

Application

18:1-06:0 NBD PE may be used as a component of liposome in cross-linking experiment and to determine M13 coat protein selectivity toward phospholipids headgroups.

Biochem/physiol Actions

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a key role as a fluorescent analog in the studies of organization and dynamics of membranes. NBD PE contributes in monitoring Red edge excitation shift (REES) effects with the unique motional and dielectric properties it possesses.

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is localized at the membrane interface. Fluorescent NBD label is covalently linked to the headgroup of phosphatidylethanolamine. Phosphoethanolamine is mostly present in brain and is the second most abundant, metabolically related aminophospholipid.

Packaging

5 mL Amber Glass Screw Cap Vial (810156C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

法规信息

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分析证书(COA)

Lot/Batch Number

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Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et Biophysica Acta, 1861(6), 1152-1161 (2019)
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
Fernandes F, et al.
Biophysical Journal, 282(52), 37298-37302 (2007)
Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Ferreira AK, et al.
Biomedicine / [Publiee Pour L'A.A.I.C.I.G.], 67(6), 481-487 (2013)
Fluorescent methods to study biological membranes, 37-50 (2012)
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochim. Biophys. Acta Gen. Subj., 1831(3), 543-554 (2013)

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