产品名称
TopFluor™ TMR PC, Avanti Research™ - A Croda Brand
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810180P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
Application
TopFluor™ TMR PC or 1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3α,4α-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3-phosphocholine may be used for the formation of lipid membranes in microarrays.
Biochem/physiol Actions
TopFluor™-labeled lipids have spectral properties similar to tetramethylrhodamine (TMR).
General description
Tetramethylrhodamine (TMR) phosphatidylcholine (PC) is a fatty acid labeled fluorescent phospholipid. Phosphatidylcholine (PC) is the most abundant phospholipid in eukaryotes. It is the prime metabolite of glycerolipid metabolism.
Packaging
5 mL Amber Glass Screw Cap Vial (810180P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Rikiya Watanabe
Biochimica et biophysica acta. General subjects, 1864(2), 129330-129330 (2019-03-31)
Micro-chamber arrays enable highly sensitive and quantitative bioassays at the single-molecule level. Accordingly, they are widely used for ultra-sensitive biomedical applications, e.g., digital PCR and digital ELISA. However, the versatility of micro-chambers is generally limited to reactions in aqueous solutions
Rikiya Watanabe et al.
Proceedings of the National Academy of Sciences of the United States of America, 115(12), 3066-3071 (2018-03-07)
Transmembrane protein 16F (TMEM16F) is a Ca2+-dependent phospholipid scramblase that translocates phospholipids bidirectionally between the leaflets of the plasma membrane. Phospholipid scrambling of TMEM16F causes exposure of phosphatidylserine in activated platelets to induce blood clotting and in differentiated osteoblasts to
Single-molecule analysis of phospholipid scrambling by TMEM16F
Rikiya W, et al.
Proceedings of the National Academy of Sciences of the USA, 115(12), 3066-3071 (2018)
Microsystem for the single molecule analysis of membrane transport proteins
Rikiya W.
Biochimica et biophysica acta. General subjects, 1864(2), 129330-129330 (2020)
A phosphatidylinositol 4, 5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing.
Mu L, et al.
Nature Communications, 9(1), 4259-4259 (2018)
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